Ling-Xiao Deng
Spinal Cord and Brain Injury Research Group,
Stark Neurosciences Research Institute,
Department of Neurological Surgery and Goodman Campbell Brain and Spine,
Spinal Cord and Brain Injury Research Group, Stark Neurosciences Research Institute, Department of Neurological Surgery and Goodman Campbell Brain and Spine
Indiana University-Indianapolis
I got my Ph.D degree in the department of Anatomy and Neuroscience in Indiana University School of Medicine and have performed research in cell transplantation and growth factor-mediated axonal regeneration and functional recovery following spinal cord injury. I has been well trained with strong technical expertise in spinal cord injury animal models, cell culture methods, cell transplantation, histology and immunohistochemistry, and behavior studies, using viral tool for neural tract tracing.Currently my research focuses on promoting the improvement of bladder function after spinal cord injury.
GDNF modifies reactive astrogliosis allowing robust axonal regeneration through Schwann cell-seeded guidance channels after spinal cord injury.
Experimental neurology Jun, 2011 | Pubmed ID: 21316362
Co-transplantation of glial restricted precursor cells and Schwann cells promotes functional recovery after spinal cord injury.
Cell transplantation Jan, 2013 | Pubmed ID: 23295060
A novel growth-promoting pathway formed by GDNF-overexpressing Schwann cells promotes propriospinal axonal regeneration, synapse formation, and partial recovery of function after spinal cord injury.
The Journal of neuroscience : the official journal of the Society for Neuroscience Mar, 2013 | Pubmed ID: 23536080
Cytosolic phospholipase A2 protein as a novel therapeutic target for spinal cord injury.
Annals of neurology May, 2014 | Pubmed ID: 24623140
Grafted bone marrow stromal cells: a contributor to glial repair after spinal cord injury.
The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry Jun, 2015 | Pubmed ID: 24777423
Schwann cell transplantation and descending propriospinal regeneration after spinal cord injury.
Brain research Sep, 2015 | Pubmed ID: 25257034
Glucocorticoid Receptor β Acts as a Co-activator of T-Cell Factor 4 and Enhances Glioma Cell Proliferation.
Molecular neurobiology Dec, 2015 | Pubmed ID: 25301232
Unilateral microinjection of acrolein into thoracic spinal cord produces acute and chronic injury and functional deficits.
Neuroscience Jun, 2016 | Pubmed ID: 27058147
Sciatic nerve regeneration in KLF7-transfected acellular nerve allografts.
Neurological research Mar, 2016 | Pubmed ID: 27093235
Transcriptional and Epigenetic Regulation in Injury-Mediated Neuronal Dendritic Plasticity.
Neuroscience bulletin Feb, 2017 | Pubmed ID: 27730386
KLF7-transfected Schwann cell graft transplantation promotes sciatic nerve regeneration.
Neuroscience 01, 2017 | Pubmed ID: 27826105
AAV-KLF7 Promotes Descending Propriospinal Neuron Axonal Plasticity after Spinal Cord Injury.
Neural plasticity , 2017 | Pubmed ID: 28884027
Inhibition of KLF7-Targeting MicroRNA 146b Promotes Sciatic Nerve Regeneration.
Neuroscience bulletin Jun, 2018 | Pubmed ID: 29356943
Remodeling of lumbar motor circuitry remote to a thoracic spinal cord injury promotes locomotor recovery.
eLife 09, 2018 | Pubmed ID: 30207538
Spinal Cord Lateral Hemisection and Asymmetric Behavioral Assessments in Adult Rats
Xiao-Jing Lin1,2,3,
Shaonan Wen2,6,
Ling-Xiao Deng3,
Heqiao Dai3,
Xiaolong Du3,
Chen Chen3,4,
Melissa J. Walker3,4,
Ting-Bao Zhao1,5,
Xiao-Ming Xu3
1Department of Spinal Cord Injury and Repair, Trauma and Orthopedics Institute of Chinese PLA, 960th Hospital, Joint Logistics Support Force of PLA,
2Institute of Military Cognition and Brain Sciences, Academy of Military Medical Sciences, Academy of Military Sciences,
3Spinal Cord and Brain Injury Research Group, Stark Neurosciences Research Institute, Department of Neurological Surgery and Goodman Campbell Brain and Spine, Indiana University School of Medicine,
4Program in Medical Neuroscience, Paul and Carole Stark Neurosciences Research Institute, Indiana University School of Medicine,
5Department of Orthopedics, the Third Affiliated Hospital, Shandong University,
6Beijing Computing Center, Beijing Academy of Science and Technology
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