Department of Biochemistry
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Two distinct populations of synaptic-like vesicles from rat brain.
Proceedings of the National Academy of Sciences of the United States of America Jan, 1998 | Pubmed ID: 9419350
The formation of an insulin-responsive vesicular cargo compartment is an early event in 3T3-L1 adipocyte differentiation.
Molecular biology of the cell May, 1999 | Pubmed ID: 10233164
Isolation and characterization of the two major intracellular Glut4 storage compartments.
The Journal of biological chemistry Mar, 2002 | Pubmed ID: 11782457
Nutrient-sensing mTOR-mediated pathway regulates leptin production in isolated rat adipocytes.
American journal of physiology. Endocrinology and metabolism Feb, 2003 | Pubmed ID: 12388166
Translocation of small preformed vesicles is responsible for the insulin activation of glucose transport in adipose cells. Evidence from the in vitro reconstitution assay.
The Journal of biological chemistry Dec, 2002 | Pubmed ID: 12393900
A long search for Glut4 activation.
Science's STKE : signal transduction knowledge environment Feb, 2003 | Pubmed ID: 12582199
Cellugyrin and synaptogyrin facilitate targeting of synaptophysin to a ubiquitous synaptic vesicle-sized compartment in PC12 cells.
The Journal of biological chemistry Nov, 2003 | Pubmed ID: 12928441
Entry of newly synthesized GLUT4 into the insulin-responsive storage compartment is GGA dependent.
The EMBO journal May, 2004 | Pubmed ID: 15116067
V-type ATPase is involved in biogenesis of GLUT4 vesicles.
American journal of physiology. Endocrinology and metabolism Sep, 2004 | Pubmed ID: 15166000
Cellugyrin induces biogenesis of synaptic-like microvesicles in PC12 cells.
The Journal of biological chemistry Feb, 2005 | Pubmed ID: 15590695
Golgi-localized, gamma-ear-containing, Arf-binding protein adaptors mediate insulin-responsive trafficking of glucose transporter 4 in 3T3-L1 adipocytes.
Molecular endocrinology (Baltimore, Md.) Aug, 2005 | Pubmed ID: 15774496
Sortilin is essential and sufficient for the formation of Glut4 storage vesicles in 3T3-L1 adipocytes.
Developmental cell Jul, 2005 | Pubmed ID: 15992544
Nutrients suppress phosphatidylinositol 3-kinase/Akt signaling via raptor-dependent mTOR-mediated insulin receptor substrate 1 phosphorylation.
Molecular and cellular biology Jan, 2006 | Pubmed ID: 16354680
Phosphatidylinositol 4-kinase type IIalpha is targeted specifically to cellugyrin-positive glucose transporter 4 vesicles.
Molecular endocrinology (Baltimore, Md.) Nov, 2006 | Pubmed ID: 16772528
The luminal Vps10p domain of sortilin plays the predominant role in targeting to insulin-responsive Glut4-containing vesicles.
The Journal of biological chemistry Mar, 2007 | Pubmed ID: 17220298
An ACAP1-containing clathrin coat complex for endocytic recycling.
The Journal of cell biology Jul, 2007 | Pubmed ID: 17664335
Isolation of GLUT4 storage vesicles.
Current protocols in cell biology Apr, 2006 | Pubmed ID: 18228488
Study of glucose uptake in adipose cells.
Methods in molecular biology (Clifton, N.J.) , 2008 | Pubmed ID: 18516571
The mammalian target of rapamycin complex 1 regulates leptin biosynthesis in adipocytes at the level of translation: the role of the 5'-untranslated region in the expression of leptin messenger ribonucleic acid.
Molecular endocrinology (Baltimore, Md.) Oct, 2008 | Pubmed ID: 18653778
Self-assembly of Glut4 storage vesicles during differentiation of 3T3-L1 adipocytes.
The Journal of biological chemistry Oct, 2008 | Pubmed ID: 18713752
The C-terminus of GLUT4 targets the transporter to the perinuclear compartment but not to the insulin-responsive vesicles.
The Biochemical journal Apr, 2009 | Pubmed ID: 19076072
FoxO1 controls insulin-dependent adipose triglyceride lipase (ATGL) expression and lipolysis in adipocytes.
The Journal of biological chemistry May, 2009 | Pubmed ID: 19297333
Cerebellar neurons possess a vesicular compartment structurally and functionally similar to Glut4-storage vesicles from peripheral insulin-sensitive tissues.
The Journal of neuroscience : the official journal of the Society for Neuroscience Apr, 2009 | Pubmed ID: 19386915
Mammalian target of rapamycin complex 1 suppresses lipolysis, stimulates lipogenesis, and promotes fat storage.
Diabetes Apr, 2010 | Pubmed ID: 20068142
The sugar is sIRVed: sorting Glut4 and its fellow travelers.
Traffic (Copenhagen, Denmark) Jun, 2011 | Pubmed ID: 21306486
Adipose triglyceride lipase: a new target in the regulation of lipolysis by insulin.
Current diabetes reviews Jul, 2011 | Pubmed ID: 21644917
SIRT1 controls lipolysis in adipocytes via FOXO1-mediated expression of ATGL.
Journal of lipid research Sep, 2011 | Pubmed ID: 21743036
The multi-level action of fatty acids on adiponectin production by fat cells.
PloS one , 2011 | Pubmed ID: 22140527
The first luminal loop confers insulin responsiveness to glucose transporter 4.
Molecular biology of the cell Mar, 2012 | Pubmed ID: 22262463
Insulin inhibits lipolysis in adipocytes via the evolutionarily conserved mTORC1-Egr1-ATGL-mediated pathway.
Molecular and cellular biology Sep, 2013 | Pubmed ID: 23858058
Insulin responsiveness of glucose transporter 4 in 3T3-L1 cells depends on the presence of sortilin.
Molecular biology of the cell Oct, 2013 | Pubmed ID: 23966466
Fat-specific protein 27 inhibits lipolysis by facilitating the inhibitory effect of transcription factor Egr1 on transcription of adipose triglyceride lipase.
The Journal of biological chemistry May, 2014 | Pubmed ID: 24742676
4E-BPs Control Fat Storage by Regulating the Expression of Egr1 and ATGL.
The Journal of biological chemistry Jul, 2015 | Pubmed ID: 25814662
The role of mTOR in lipid homeostasis and diabetes progression.
Current opinion in endocrinology, diabetes, and obesity Oct, 2015 | Pubmed ID: 26241026
Sortilin and retromer mediate retrograde transport of Glut4 in 3T3-L1 adipocytes.
Molecular biology of the cell Jun, 2017 | Pubmed ID: 28450454
Mammalian target of rapamycin complex 1 and FoxO1 in the transcriptional control of lipolysis and de novo lipogenesis.
Current opinion in endocrinology, diabetes, and obesity Oct, 2017 | Pubmed ID: 28841634
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