Konstantin V. Kandror

Two distinct populations of synaptic-like vesicles from rat brain.

The formation of an insulin-responsive vesicular cargo compartment is an early event in 3T3-L1 adipocyte differentiation.

Isolation and characterization of the two major intracellular Glut4 storage compartments.

Nutrient-sensing mTOR-mediated pathway regulates leptin production in isolated rat adipocytes.

Translocation of small preformed vesicles is responsible for the insulin activation of glucose transport in adipose cells. Evidence from the in vitro reconstitution assay.

A long search for Glut4 activation.

Cellugyrin and synaptogyrin facilitate targeting of synaptophysin to a ubiquitous synaptic vesicle-sized compartment in PC12 cells.

Entry of newly synthesized GLUT4 into the insulin-responsive storage compartment is GGA dependent.

V-type ATPase is involved in biogenesis of GLUT4 vesicles.

Cellugyrin induces biogenesis of synaptic-like microvesicles in PC12 cells.

Golgi-localized, gamma-ear-containing, Arf-binding protein adaptors mediate insulin-responsive trafficking of glucose transporter 4 in 3T3-L1 adipocytes.

Sortilin is essential and sufficient for the formation of Glut4 storage vesicles in 3T3-L1 adipocytes.

Nutrients suppress phosphatidylinositol 3-kinase/Akt signaling via raptor-dependent mTOR-mediated insulin receptor substrate 1 phosphorylation.

Phosphatidylinositol 4-kinase type IIalpha is targeted specifically to cellugyrin-positive glucose transporter 4 vesicles.

The luminal Vps10p domain of sortilin plays the predominant role in targeting to insulin-responsive Glut4-containing vesicles.

An ACAP1-containing clathrin coat complex for endocytic recycling.

Isolation of GLUT4 storage vesicles.

Study of glucose uptake in adipose cells.

The mammalian target of rapamycin complex 1 regulates leptin biosynthesis in adipocytes at the level of translation: the role of the 5'-untranslated region in the expression of leptin messenger ribonucleic acid.

Self-assembly of Glut4 storage vesicles during differentiation of 3T3-L1 adipocytes.

The C-terminus of GLUT4 targets the transporter to the perinuclear compartment but not to the insulin-responsive vesicles.

FoxO1 controls insulin-dependent adipose triglyceride lipase (ATGL) expression and lipolysis in adipocytes.

Cerebellar neurons possess a vesicular compartment structurally and functionally similar to Glut4-storage vesicles from peripheral insulin-sensitive tissues.

Mammalian target of rapamycin complex 1 suppresses lipolysis, stimulates lipogenesis, and promotes fat storage.

The sugar is sIRVed: sorting Glut4 and its fellow travelers.

Adipose triglyceride lipase: a new target in the regulation of lipolysis by insulin.

SIRT1 controls lipolysis in adipocytes via FOXO1-mediated expression of ATGL.

The multi-level action of fatty acids on adiponectin production by fat cells.

The first luminal loop confers insulin responsiveness to glucose transporter 4.

Insulin inhibits lipolysis in adipocytes via the evolutionarily conserved mTORC1-Egr1-ATGL-mediated pathway.

Insulin responsiveness of glucose transporter 4 in 3T3-L1 cells depends on the presence of sortilin.

Fat-specific protein 27 inhibits lipolysis by facilitating the inhibitory effect of transcription factor Egr1 on transcription of adipose triglyceride lipase.

4E-BPs Control Fat Storage by Regulating the Expression of Egr1 and ATGL.

The role of mTOR in lipid homeostasis and diabetes progression.

Sortilin and retromer mediate retrograde transport of Glut4 in 3T3-L1 adipocytes.

Mammalian target of rapamycin complex 1 and FoxO1 in the transcriptional control of lipolysis and de novo lipogenesis.