School of Biomedical Sciences,
Institute of Vascular Medicine,
Li Ka Shing Institute of Health Sciences,
School of Biomedical Sciences, Institute of Vascular Medicine, Li Ka Shing Institute of Health Sciences
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Angiotensin II type 1 receptor-dependent oxidative stress mediates endothelial dysfunction in type 2 diabetic mice.
Antioxidants & redox signaling Sep, 2010 | Pubmed ID: 20136508
Endothelial dysfunction: the common consequence in diabetes and hypertension.
Journal of cardiovascular pharmacology Apr, 2010 | Pubmed ID: 20422734
4-aminopyridine-sensitive K+ channels contributes to NaHS-induced membrane hyperpolarization and relaxation in the rat coronary artery.
Vascular pharmacology Sep-Oct, 2010 | Pubmed ID: 20430111
Bone morphogenic protein-4 impairs endothelial function through oxidative stress-dependent cyclooxygenase-2 upregulation: implications on hypertension.
Circulation research Oct, 2010 | Pubmed ID: 20724703
Prostaglandins in action indispensable roles of cyclooxygenase-1 and -2 in endothelium-dependent contractions.
Advances in pharmacology (San Diego, Calif.) , 2010 | Pubmed ID: 21081215
Telmisartan inhibits vasoconstriction via PPARγ-dependent expression and activation of endothelial nitric oxide synthase.
Cardiovascular research Apr, 2011 | Pubmed ID: 21156825
AVE3085, an enhancer of endothelial nitric oxide synthase, restores endothelial function and reduces blood pressure in spontaneously hypertensive rats.
British journal of pharmacology Jul, 2011 | Pubmed ID: 21385179
Inhibition of renin-angiotensin system reverses endothelial dysfunction and oxidative stress in estrogen deficient rats.
PloS one , 2011 | Pubmed ID: 21479266
Effect of phytosterols and their oxidation products on lipoprotein profiles and vascular function in hamster fed a high cholesterol diet.
Atherosclerosis Nov, 2011 | Pubmed ID: 21719014
Adiponectin is required for PPARγ-mediated improvement of endothelial function in diabetic mice.
Cell metabolism Jul, 2011 | Pubmed ID: 21723508
Endothelial nitric oxide synthase enhancer reduces oxidative stress and restores endothelial function in db/db mice.
Cardiovascular research Nov, 2011 | Pubmed ID: 21875904
Oxidative stress-dependent cyclooxygenase-2-derived prostaglandin f(2α) impairs endothelial function in renovascular hypertensive rats.
Antioxidants & redox signaling Feb, 2012 | Pubmed ID: 21951274
Raloxifene improves vascular reactivity in pressurized septal coronary arteries of ovariectomized hamsters fed cholesterol diet.
Pharmacological research : the official journal of the Italian Pharmacological Society Feb, 2012 | Pubmed ID: 22005391
Bone morphogenic protein-4 induces endothelial cell apoptosis through oxidative stress-dependent p38MAPK and JNK pathway.
Journal of molecular and cellular cardiology Jan, 2012 | Pubmed ID: 22064324
NaHS relaxes rat cerebral artery in vitro via inhibition of l-type voltage-sensitive Ca(2+) channel.
Pharmacological research : the official journal of the Italian Pharmacological Society Feb, 2012 | Pubmed ID: 22133671
Capsaicinoids lower plasma cholesterol and improve endothelial function in hamsters.
European journal of nutrition Mar, 2012 | Pubmed ID: 22466858
Chronic cranberry juice consumption restores cholesterol profiles and improves endothelial function in ovariectomized rats.
European journal of nutrition Jul, 2012 | Pubmed ID: 22836513
Dipeptidyl peptidase 4 inhibitor sitagliptin protects endothelial function in hypertension through a glucagon-like peptide 1-dependent mechanism.
Hypertension Sep, 2012 | Pubmed ID: 22868389
PPARδ Activation Protects Endothelial Function in Diabetic Mice.
Diabetes Dec, 2012 | Pubmed ID: 22933110
Fo Shou San, an ancient Chinese herbal decoction, protects endothelial function through increasing endothelial nitric oxide synthase activity.
PloS one , 2012 | Pubmed ID: 23284736
Menthol relaxes rat aortae, mesenteric and coronary arteries by inhibiting calcium influx.
European journal of pharmacology Feb, 2013 | Pubmed ID: 23380688
Boldine improves endothelial function in diabetic db/db mice through inhibition of angiotensin II-mediated BMP4-oxidative stress cascade.
British journal of pharmacology Nov, 2013 | Pubmed ID: 23992296
Pleiotropic effects of peroxisome proliferator-activated receptor γ and δ in vascular diseases.
Circulation journal : official journal of the Japanese Circulation Society , 2013 | Pubmed ID: 24107399
Inhibition of bone morphogenic protein 4 restores endothelial function in db/db diabetic mice.
Arteriosclerosis, thrombosis, and vascular biology Jan, 2014 | Pubmed ID: 24202302
Uncoupling protein-2 mediates DPP-4 inhibitor-induced restoration of endothelial function in hypertension through reducing oxidative stress.
Antioxidants & redox signaling Oct, 2014 | Pubmed ID: 24328731
Metformin protects endothelial function in diet-induced obese mice by inhibition of endoplasmic reticulum stress through 5' adenosine monophosphate-activated protein kinase-peroxisome proliferator-activated receptor δ pathway.
Arteriosclerosis, thrombosis, and vascular biology Apr, 2014 | Pubmed ID: 24482374
Rosiglitazone Attenuated Endothelin-1-Induced Vasoconstriction of Pulmonary Arteries in the Rat Model of Pulmonary Arterial Hypertension via Differential Regulation of ET-1 Receptors.
PPAR research , 2014 | Pubmed ID: 24701204
The peroxisome proliferator-activated receptors in cardiovascular diseases: experimental benefits and clinical challenges.
British journal of pharmacology Dec, 2015 | Pubmed ID: 25438608
Unconjugated bilirubin mediates heme oxygenase-1-induced vascular benefits in diabetic mice.
Diabetes May, 2015 | Pubmed ID: 25475440
Upregulation of Angiotensin (1-7)-Mediated Signaling Preserves Endothelial Function Through Reducing Oxidative Stress in Diabetes.
Antioxidants & redox signaling Oct, 2015 | Pubmed ID: 25867182
Black tea protects against hypertension-associated endothelial dysfunction through alleviation of endoplasmic reticulum stress.
Scientific reports May, 2015 | Pubmed ID: 25976123
A revisit on the renin-angiotensin system in cardiovascular biology.
Trends in cardiovascular medicine Apr, 2016 | Pubmed ID: 26212445
Chronic black tea extract consumption improves endothelial function in ovariectomized rats.
European journal of nutrition Aug, 2016 | Pubmed ID: 26276555
Bone Morphogenic Protein 4-Smad-Induced Upregulation of Platelet-Derived Growth Factor AA Impairs Endothelial Function.
Arteriosclerosis, thrombosis, and vascular biology Mar, 2016 | Pubmed ID: 26769046
E-selectin-targeting delivery of microRNAs by microparticles ameliorates endothelial inflammation and atherosclerosis.
Scientific reports Mar, 2016 | Pubmed ID: 26956647
Melamine Impairs Renal and Vascular Function in Rats.
Scientific reports 06, 2016 | Pubmed ID: 27324576
Reactive Oxygen Species, Endoplasmic Reticulum Stress and Mitochondrial Dysfunction: The Link with Cardiac Arrhythmogenesis.
Frontiers in physiology , 2016 | Pubmed ID: 27536244
PPARδ Is Required for Exercise to Attenuate Endoplasmic Reticulum Stress and Endothelial Dysfunction in Diabetic Mice.
Diabetes 02, 2017 | Pubmed ID: 27856609
Integrin-YAP/TAZ-JNK cascade mediates atheroprotective effect of unidirectional shear flow.
Nature Dec, 2016 | Pubmed ID: 27926730
Myeloid deletion increases monocyte recruitment and worsens atherosclerosis.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 03, 2017 | Pubmed ID: 27927724
Generation of Human Liver Chimeric Mice with Hepatocytes from Familial Hypercholesterolemia Induced Pluripotent Stem Cells.
Stem cell reports 03, 2017 | Pubmed ID: 28262545
Inhibition of miR-92a Suppresses Oxidative Stress and Improves Endothelial Function by Upregulating Heme Oxygenase-1 in db/db Mice.
Antioxidants & redox signaling 02, 2018 | Pubmed ID: 28683566
Comprehensive Analysis of Acylcarnitine Species in db/db Mouse Using a Novel Method of High-Resolution Parallel Reaction Monitoring Reveals Widespread Metabolic Dysfunction Induced by Diabetes.
Analytical chemistry Oct, 2017 | Pubmed ID: 28859482
Recent Advances in Managing Atherosclerosis via Nanomedicine.
Small (Weinheim an der Bergstrasse, Germany) Jan, 2018 | Pubmed ID: 29239134
Regulatory T Cells Promote Apelin-Mediated Sprouting Angiogenesis in Type 2 Diabetes.
Cell reports Aug, 2018 | Pubmed ID: 30089270
Uncoupling Protein 2 in Cardiovascular Health and Disease.
Frontiers in physiology , 2018 | Pubmed ID: 30116205
Jiayin Yang*,1,2,6,
Lai-Yung Wong*,2,
Xiao-Yu Tian*,3,
Rui Wei1,2,
Wing-Hon Lai2,
Ka-Wing Au2,
Zhiwei Luo4,5,
Carl Ward4,5,
Wai-In Ho2,
David P. Ibañez4,5,
Hao Liu4,5,
Xichen Bao4,5,
Baoming Qin4,5,
Yu Huang3,
Miguel A. Esteban4,5,7,
Hung-Fat Tse1,2,6,7
1Department of Medicine, University of Hong Kong-Shenzhen Hospital,
2The Cardiology Division, Department of Medicine, Li Ka Shing Faculty of Medicine, University of Hong Kong,
3School of Biomedical Sciences, Institute of Vascular Medicine, Li Ka Shing Institute of Health Sciences, Chinese University of Hong Kong,
4Key Laboratory of Regenerative Biology of the Chinese Academy of Sciences, Joint School of Life Sciences, Guangzhou Institutes of Biomedicine and Health and Guangzhou Medical University,
5Laboratory of RNA, Chromatin, and Human Disease, CAS Key Laboratory of Regenerative Biology and Guangdong Provincial Key Laboratory of Stem Cells and Regenerative Medicine, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences,
6Research Centre of Heart, Brain, Hormone, and Healthy Ageing, Li Ka Shing Faculty of Medicine, University of Hong Kong,
7Hong Kong-Guangdong Stem Cell and Regenerative Medicine Research Centre, University of Hong Kong and Guangzhou Institutes of Biomedicine and Health
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