Division of Pulmonary,
Critical Care,
and Sleep Medicine,
Department of Internal Medicine,
Division of Pulmonary, Critical Care, and Sleep Medicine, Department of Internal Medicine
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Simvastatin inhibits airway hyperreactivity: implications for the mevalonate pathway and beyond.
American journal of respiratory and critical care medicine Oct, 2009 | Pubmed ID: 19608720
Statin drugs, metabolic pathways, and asthma: a therapeutic opportunity needing further research.
Drug metabolism letters Jan, 2011 | Pubmed ID: 21198438
The Asthma-COPD Overlap Syndrome: A Common Clinical Problem in the Elderly.
Journal of allergy , 2011 | Pubmed ID: 22121384
Simvastatin inhibits smoke-induced airway epithelial injury: implications for COPD therapy.
The European respiratory journal Apr, 2014 | Pubmed ID: 24687675
Intratracheal instillation of pravastatin for the treatment of murine allergic asthma: a lung-targeted approach to deliver statins.
Physiological reports May, 2015 | Pubmed ID: 25969462
Editorial (Thematic Issue: New Insights into a Classical Pathway: Key Roles of the Mevalonate Cascade in Different Diseases (Part I)).
Current molecular pharmacology , 2017 | Pubmed ID: 26768962
Paradigms in chronic obstructive pulmonary disease: phenotypes, immunobiology, and therapy with a focus on vascular disease.
Journal of investigative medicine : the official publication of the American Federation for Clinical Research 08, 2017 | Pubmed ID: 28258130
Mevalonate Cascade Inhibition by Simvastatin Induces the Intrinsic Apoptosis Pathway via Depletion of Isoprenoids in Tumor Cells.
Scientific reports 03, 2017 | Pubmed ID: 28344327
Farnesyltransferase Inhibition Exacerbates Eosinophilic Inflammation and Airway Hyperreactivity in Mice with Experimental Asthma: The Complex Roles of Ras GTPase and Farnesylpyrophosphate in Type 2 Allergic Inflammation.
Journal of immunology (Baltimore, Md. : 1950) Jun, 2018 | Pubmed ID: 29703864
Javad Alizadeh1,2,
Shahla Shojaei1,2,3,
Simone da Silva Rosa1,
Adel Rezaei Moghadam1,2,
Amir A. Zeki4,
Mohammad Hashemi5,
Marek J. Los6,7,8,
Joseph W. Gordon1,9,
Saeid Ghavami1,2,10
1Department of Human Anatomy and Cell Science, Rady Faculty of Health Sciences, Max Rady College of Medicine, University of Manitoba,
2Biology of Breathing Theme, Children Hospital Research Institute of Manitoba, University of Manitoba,
3Department of Biochemistry, School of Pharmacy and Pharmaceutical Sciences, Isfahan University of Medical Sciences,
4Division of Pulmonary, Critical Care, and Sleep Medicine, Department of Internal Medicine, Center for Comparative Respiratory Biology and Medicine,
5Department of Clinical Biochemistry, School of Medicine, Zahedan University of Medical Sciences,
6Department of Molecular Biology, School of Pharmacy with the Division of Laboratory Medicine in Sosnowiec, Medical University of Silesia,
7Centre de biophysique moléculaire - UPR 4301, Centre national de la recherche scientifique (CNRS) CS80054,
8, LinkoCare Life Sciences AB,
9College of Nursing and Children's Hospital Research Institute of Manitoba, Rady Faculty of Health Sciences, University of Manitoba,
10Health Policy Research Center, Institute of Health, Shiraz University of Medical Sciences
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