Department of Physiology and Biophysics
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Imaging superoxide flash and metabolism-coupled mitochondrial permeability transition in living animals.
Cell research Sep, 2011 | Pubmed ID: 21556035
Store-operated Ca(2+) entry (SOCE) contributes to normal skeletal muscle contractility in young but not in aged skeletal muscle.
Aging Jun, 2011 | Pubmed ID: 21666285
Stimulatory and Inhibitory Functions of the R Domain on CFTR Chloride Channel.
News in physiological sciences : an international journal of physiology produced jointly by the International Union of Physiological Sciences and the American Physiological Society Jun, 2000 | Pubmed ID: 11390899
The transmembrane segment of ryanodine receptor contains an intracellular membrane retention signal for Ca(2+) release channel.
The Journal of biological chemistry Mar, 2002 | Pubmed ID: 11779857
A short segment of the R domain of cystic fibrosis transmembrane conductance regulator contains channel stimulatory and inhibitory activities that are separable by sequence modification.
The Journal of biological chemistry Jun, 2002 | Pubmed ID: 11950844
Dysfunction of store-operated calcium channel in muscle cells lacking mg29.
Nature cell biology May, 2002 | Pubmed ID: 11988740
Identification of a dantrolene-binding sequence on the skeletal muscle ryanodine receptor.
The Journal of biological chemistry Sep, 2002 | Pubmed ID: 12167662
Ca(2+)-dependent interaction between FKBP12 and calcineurin regulates activity of the Ca(2+) release channel in skeletal muscle.
Biophysical journal Nov, 2002 | Pubmed ID: 12414688
A retrograde signal from calsequestrin for the regulation of store-operated Ca2+ entry in skeletal muscle.
The Journal of biological chemistry Jan, 2003 | Pubmed ID: 12419813
Junctional membrane structure and store operated calcium entry in muscle cells.
Frontiers in bioscience : a journal and virtual library Jan, 2003 | Pubmed ID: 12456355
Targeting of protein kinase A by muscle A kinase-anchoring protein (mAKAP) regulates phosphorylation and function of the skeletal muscle ryanodine receptor.
The Journal of biological chemistry Jul, 2003 | Pubmed ID: 12709444
Retrograde activation of store-operated calcium channel.
Cell calcium May-Jun, 2003 | Pubmed ID: 12765683
Intermolecular interaction between R domains of cystic fibrosis transmembrane conductance regulator.
American journal of respiratory cell and molecular biology Feb, 2004 | Pubmed ID: 12933354
Negatively charged amino acids within the intraluminal loop of ryanodine receptor are involved in the interaction with triadin.
The Journal of biological chemistry Feb, 2004 | Pubmed ID: 14638677
Co-expression of MG29 and ryanodine receptor leads to apoptotic cell death: effect mediated by intracellular Ca2+ release.
The Journal of biological chemistry May, 2004 | Pubmed ID: 15039443
Membrane topology and membrane retention of the ryanodine receptor calcium release channel.
Cell biochemistry and biophysics , 2004 | Pubmed ID: 15054223
Nuclear translocation of cytochrome c during apoptosis.
The Journal of biological chemistry Jun, 2004 | Pubmed ID: 15073175
The role of glycine residues in the function of human organic anion transporter 4.
Molecular pharmacology May, 2004 | Pubmed ID: 15102942
Calcium-dependent facilitation and graded deactivation of store-operated calcium entry in fetal skeletal muscle.
Biophysical journal Jul, 2004 | Pubmed ID: 15240463
Mutational analysis of histidine residues in human organic anion transporter 4 (hOAT4).
The Biochemical journal Nov, 2004 | Pubmed ID: 15291761
The role of N-linked glycosylation in protein folding, membrane targeting, and substrate binding of human organic anion transporter hOAT4.
Molecular pharmacology Mar, 2005 | Pubmed ID: 15576633
Probing a putative dantrolene-binding site on the cardiac ryanodine receptor.
The Biochemical journal May, 2005 | Pubmed ID: 15656791
A rapid and efficient PCR-based mutagenesis method applicable to cell physiology study.
American journal of physiology. Cell physiology Jun, 2005 | Pubmed ID: 15659713
Uncontrolled calcium sparks act as a dystrophic signal for mammalian skeletal muscle.
Nature cell biology May, 2005 | Pubmed ID: 15834406
Enhanced resistance to fatigue and altered calcium handling properties of sarcalumenin knockout mice.
Physiological genomics Sep, 2005 | Pubmed ID: 15998745
Inhibition of intestinal tumorigenesis in Apcmin/+ mice by (-)-epigallocatechin-3-gallate, the major catechin in green tea.
Cancer research Nov, 2005 | Pubmed ID: 16288056
Uncoupling store-operated Ca2+ entry and altered Ca2+ release from sarcoplasmic reticulum through silencing of junctophilin genes.
Biophysical journal Jun, 2006 | Pubmed ID: 16565048
The presenilin-2 loop peptide perturbs intracellular Ca2+ homeostasis and accelerates apoptosis.
The Journal of biological chemistry Jun, 2006 | Pubmed ID: 16603547
Butylated hydroxyanisole regulates ARE-mediated gene expression via Nrf2 coupled with ERK and JNK signaling pathway in HepG2 cells.
Molecular carcinogenesis Nov, 2006 | Pubmed ID: 16739127
Mechanism of action of isothiocyanates: the induction of ARE-regulated genes is associated with activation of ERK and JNK and the phosphorylation and nuclear translocation of Nrf2.
Molecular cancer therapeutics Aug, 2006 | Pubmed ID: 16928811
Muscle aging is associated with compromised Ca2+ spark signaling and segregated intracellular Ca2+ release.
The Journal of cell biology Aug, 2006 | Pubmed ID: 16943181
Azumolene inhibits a component of store-operated calcium entry coupled to the skeletal muscle ryanodine receptor.
The Journal of biological chemistry Nov, 2006 | Pubmed ID: 16945924
Determination of the external loops and the cellular orientation of the N- and the C-termini of the human organic anion transporter hOAT1.
The Biochemical journal Jan, 2007 | Pubmed ID: 17014423
Conformation-dependent stability of junctophilin 1 (JP1) and ryanodine receptor type 1 (RyR1) channel complex is mediated by their hyper-reactive thiols.
The Journal of biological chemistry Mar, 2007 | Pubmed ID: 17237236
Systemic ablation of RyR3 alters Ca2+ spark signaling in adult skeletal muscle.
Cell calcium Dec, 2007 | Pubmed ID: 17412417
Mutations in JPH2-encoded junctophilin-2 associated with hypertrophic cardiomyopathy in humans.
Journal of molecular and cellular cardiology Jun, 2007 | Pubmed ID: 17509612
TRIC channels are essential for Ca2+ handling in intracellular stores.
Nature Jul, 2007 | Pubmed ID: 17611541
The tail-anchoring domain of Bfl1 and HCCS1 targets mitochondrial membrane permeability to induce apoptosis.
Journal of cell science Aug, 2007 | Pubmed ID: 17666431
Immuno-proteomic approach to excitation--contraction coupling in skeletal and cardiac muscle: molecular insights revealed by the mitsugumins.
Cell calcium Jan, 2008 | Pubmed ID: 18061662
Overexpression of Bax induces down-regulation of store-operated calcium entry in prostate cancer cells.
Journal of cellular physiology Jul, 2008 | Pubmed ID: 18247359
Altered Ca2+ sparks in aging skeletal and cardiac muscle.
Ageing research reviews Jul, 2008 | Pubmed ID: 18272434
Compromised store-operated Ca2+ entry in aged skeletal muscle.
Aging cell Aug, 2008 | Pubmed ID: 18505477
Genetic evidence for functional role of ryanodine receptor 1 in pulmonary artery smooth muscle cells.
Pflügers Archiv : European journal of physiology Feb, 2009 | Pubmed ID: 18663468
Organic anion transporter OAT1 undergoes constitutive and protein kinase C-regulated trafficking through a dynamin- and clathrin-dependent pathway.
The Journal of biological chemistry Nov, 2008 | Pubmed ID: 18818201
Protein kinase C-epsilon regulates local calcium signaling in airway smooth muscle cells.
American journal of respiratory cell and molecular biology Jun, 2009 | Pubmed ID: 19011160
MG53 regulates membrane budding and exocytosis in muscle cells.
The Journal of biological chemistry Jan, 2009 | Pubmed ID: 19029292
MG53 nucleates assembly of cell membrane repair machinery.
Nature cell biology Jan, 2009 | Pubmed ID: 19043407
The amino-terminal peptide of Bax perturbs intracellular Ca2+ homeostasis to enhance apoptosis in prostate cancer cells.
American journal of physiology. Cell physiology Feb, 2009 | Pubmed ID: 19091958
Mitsugumin 53-mediated maintenance of K+ currents in cardiac myocytes.
Channels (Austin, Tex.) Jan-Feb, 2009 | Pubmed ID: 19202355
Glutamate at position 227 of junctophilin-2 is involved in binding to TRPC3.
Molecular and cellular biochemistry Aug, 2009 | Pubmed ID: 19277847
Membrane repair defects in muscular dystrophy are linked to altered interaction between MG53, caveolin-3, and dysferlin.
The Journal of biological chemistry Jun, 2009 | Pubmed ID: 19380584
NAADP mobilizes calcium from acidic organelles through two-pore channels.
Nature May, 2009 | Pubmed ID: 19387438
The acid test: the discovery of two-pore channels (TPCs) as NAADP-gated endolysosomal Ca(2+) release channels.
Pflügers Archiv : European journal of physiology Sep, 2009 | Pubmed ID: 19475418
Mitsugumin 53 (MG53) facilitates vesicle trafficking in striated muscle to contribute to cell membrane repair.
Communicative & integrative biology May, 2009 | Pubmed ID: 19641737
Calcium signaling via two-pore channels: local or global, that is the question.
American journal of physiology. Cell physiology Mar, 2010 | Pubmed ID: 20018950
Impaired interaction between skeletal ryanodine receptors in malignant hyperthermia.
Integrative biology : quantitative biosciences from nano to macro Sep, 2009 | Pubmed ID: 20023768
S165F mutation of junctophilin 2 affects Ca2+ signalling in skeletal muscle.
The Biochemical journal Apr, 2010 | Pubmed ID: 20095964
TPCs: Endolysosomal channels for Ca2+ mobilization from acidic organelles triggered by NAADP.
FEBS letters May, 2010 | Pubmed ID: 20159015
Cardioprotection of ischemia/reperfusion injury by cholesterol-dependent MG53-mediated membrane repair.
Circulation research Jul, 2010 | Pubmed ID: 20466981
2-Methoxyoestradiol inhibits glucose transport in rodent skeletal muscle.
Experimental physiology Aug, 2010 | Pubmed ID: 20472648
MG53 constitutes a primary determinant of cardiac ischemic preconditioning.
Circulation Jun, 2010 | Pubmed ID: 20516375
Two-pore channels for integrative Ca signaling.
Communicative & integrative biology Jan, 2010 | Pubmed ID: 20539775
Bid agonist regulates murine hepatocyte proliferation by controlling endoplasmic reticulum calcium homeostasis.
Hepatology (Baltimore, Md.) Jul, 2010 | Pubmed ID: 20578150
Charade of the SR K+-channel: two ion-channels, TRIC-A and TRIC-B, masquerade as a single K+-channel.
Biophysical journal Jul, 2010 | Pubmed ID: 20643059
Increased store-operated Ca2+ entry in skeletal muscle with reduced calsequestrin-1 expression.
Biophysical journal Sep, 2010 | Pubmed ID: 20816068
Ca2+ overload and sarcoplasmic reticulum instability in tric-a null skeletal muscle.
The Journal of biological chemistry Nov, 2010 | Pubmed ID: 20858894
Impaired Orai1-mediated resting Ca2+ entry reduces the cytosolic [Ca2+] and sarcoplasmic reticulum Ca2+ loading in quiescent junctophilin 1 knock-out myotubes.
The Journal of biological chemistry Dec, 2010 | Pubmed ID: 20937810
An emerging role for NAADP-mediated Ca2+ signaling in the pancreatic β-cell.
Islets Sep-Oct, 2010 | Pubmed ID: 21099331
Amphipathic tail-anchoring peptide and Bcl-2 homology domain-3 (BH3) peptides from Bcl-2 family proteins induce apoptosis through different mechanisms.
The Journal of biological chemistry Mar, 2011 | Pubmed ID: 21189256
Junctophilin-2 expression silencing causes cardiocyte hypertrophy and abnormal intracellular calcium-handling.
Circulation. Heart failure Mar, 2011 | Pubmed ID: 21216834
Cyclic adenosine diphosphate ribose activates ryanodine receptors, whereas NAADP activates two-pore domain channels.
The Journal of biological chemistry Mar, 2011 | Pubmed ID: 21216967
MG53 participates in ischaemic postconditioning through the RISK signalling pathway.
Cardiovascular research Jul, 2011 | Pubmed ID: 21285295
Polymerase transcriptase release factor (PTRF) anchors MG53 protein to cell injury site for initiation of membrane repair.
The Journal of biological chemistry Apr, 2011 | Pubmed ID: 21343302
Dysferlin, annexin A1, and mitsugumin 53 are upregulated in muscular dystrophy and localize to longitudinal tubules of the T-system with stretch.
Journal of neuropathology and experimental neurology Apr, 2011 | Pubmed ID: 21412170
tBHQ-induced HO-1 expression is mediated by calcium through regulation of Nrf2 binding to enhancer and polymerase II to promoter region of HO-1.
Chemical research in toxicology May, 2011 | Pubmed ID: 21443188
Ataxin-1 and Brother of ataxin-1 are components of the Notch signalling pathway.
EMBO reports May, 2011 | Pubmed ID: 21475249
A versatile single-plasmid system for tissue-specific and inducible control of gene expression in transgenic mice.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology Aug, 2011 | Pubmed ID: 21518849
Redox-dependent oligomerization through a leucine zipper motif is essential for MG53-mediated cell membrane repair.
American journal of physiology. Cell physiology Jul, 2011 | Pubmed ID: 21525429
Molecular architecture of Ca2+ signaling control in muscle and heart cells.
Channels (Austin, Tex.) Sep, 2011 | Pubmed ID: 21712647
Mitochondrial calcium uptake regulates rapid calcium transients in skeletal muscle during excitation-contraction (E-C) coupling.
The Journal of biological chemistry Sep, 2011 | Pubmed ID: 21795684
Disrupted membrane structure and intracellular Ca²⺠signaling in adult skeletal muscle with acute knockdown of Bin1.
PloS one , 2011 | Pubmed ID: 21984944
Detection of calcium sparks in intact and permeabilized skeletal muscle fibers.
Methods in molecular biology (Clifton, N.J.) , 2012 | Pubmed ID: 22130850
Nonmuscle myosin IIA facilitates vesicle trafficking for MG53-mediated cell membrane repair.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology Jan, 2012 | Pubmed ID: 22253476
Enhancing Muscle Membrane Repair by Gene Delivery of MG53 Ameliorates Muscular Dystrophy and Heart Failure in δ-Sarcoglycan-deficient Hamsters.
Molecular therapy : the journal of the American Society of Gene Therapy Feb, 2012 | Pubmed ID: 22314291
Hypertrophy in skeletal myotubes induced by junctophilin-2 mutant, Y141H, involves an increase in store-operated Ca2+ entry via Orai1.
The Journal of biological chemistry Apr, 2012 | Pubmed ID: 22389502
Recombinant MG53 protein modulates therapeutic cell membrane repair in treatment of muscular dystrophy.
Science translational medicine Jun, 2012 | Pubmed ID: 22723464
Switch from ER-mitochondrial to SR-mitochondrial calcium coupling during muscle differentiation.
Cell calcium Nov, 2012 | Pubmed ID: 22784666
TRIM50 Protein Regulates Vesicular Trafficking for Acid Secretion in Gastric Parietal Cells.
The Journal of biological chemistry Sep, 2012 | Pubmed ID: 22872646
Mitsugumin 53 attenuates the activity of sarcoplasmic reticulum Ca(2+)-ATPase 1a (SERCA1a) in skeletal muscle.
Biochemical and biophysical research communications Oct, 2012 | Pubmed ID: 23103543
The Mesobuthus martensii genome reveals the molecular diversity of scorpion toxins.
Cell & bioscience Jan, 2014 | Pubmed ID: 24383941
The effect of recombinant human MG53 protein on tourniquet-induced ischemia reperfusion injury in rat muscle.
Muscle & nerve Jan, 2014 | Pubmed ID: 24395153
Store-operated Ca2+ entry in muscle physiology and diseases.
BMB reports Feb, 2014 | Pubmed ID: 24411466
Trimeric intracellular cation channels and sarcoplasmic/endoplasmic reticulum calcium homeostasis.
Circulation research Feb, 2014 | Pubmed ID: 24526676
Core-shell nanoparticle-based peptide therapeutics and combined hyperthermia for enhanced cancer cell apoptosis.
ACS nano Sep, 2014 | Pubmed ID: 25133971
Amphipathic tail-anchoring peptide is a promising therapeutic agent for prostate cancer treatment.
Oncotarget Sep, 2014 | Pubmed ID: 25245280
Cell membrane damage is involved in the impaired survival of bone marrow stem cells by oxidized low-density lipoprotein.
Journal of cellular and molecular medicine Dec, 2014 | Pubmed ID: 25256620
Organelle-specific subunit interactions of the vertebrate two-pore channel family.
The Journal of biological chemistry Jan, 2015 | Pubmed ID: 25451935
Lysosomal two-pore channel subtype 2 (TPC2) regulates skeletal muscle autophagic signaling.
The Journal of biological chemistry Feb, 2015 | Pubmed ID: 25480788
Open Sesame: treasure in store-operated calcium entry pathway for cancer therapy.
Science China. Life sciences Jan, 2015 | Pubmed ID: 25481035
Cardioprotection of recombinant human MG53 protein in a porcine model of ischemia and reperfusion injury.
Journal of molecular and cellular cardiology Mar, 2015 | Pubmed ID: 25533937
Dysfunction in the βII spectrin-dependent cytoskeleton underlies human arrhythmia.
Circulation Feb, 2015 | Pubmed ID: 25632041
Amelioration of ischemia-reperfusion-induced muscle injury by the recombinant human MG53 protein.
Muscle & nerve Nov, 2015 | Pubmed ID: 25703692
3D multifocus astigmatism and compressed sensing (3D MACS) based superresolution reconstruction.
Biomedical optics express Mar, 2015 | Pubmed ID: 25798314
Zinc Binding to MG53 Protein Facilitates Repair of Injury to Cell Membranes.
The Journal of biological chemistry May, 2015 | Pubmed ID: 25869134
Modulation of wound healing and scar formation by MG53 protein-mediated cell membrane repair.
The Journal of biological chemistry Oct, 2015 | Pubmed ID: 26306047
CRISPR-mediated Genome Editing Restores Dystrophin Expression and Function in mdx Mice.
Molecular therapy : the journal of the American Society of Gene Therapy Mar, 2016 | Pubmed ID: 26449883
Quantifying Drug-Induced Nanomechanics and Mechanical Effects to Single Cardiomyocytes for Optimal Drug Administration To Minimize Cardiotoxicity.
Langmuir : the ACS journal of surfaces and colloids Feb, 2016 | Pubmed ID: 26738425
Autophagy, Innate Immunity and Tissue Repair in Acute Kidney Injury.
International journal of molecular sciences May, 2016 | Pubmed ID: 27153058
Dual function of MG53 in membrane repair and insulin signaling.
BMB reports Aug, 2016 | Pubmed ID: 27174502
Absence of physiological Ca transients is an initial trigger for mitochondrial dysfunction in skeletal muscle following denervation.
Skeletal muscle 04, 2017 | Pubmed ID: 28395670
In Vivo Genome Editing Restores Dystrophin Expression and Cardiac Function in Dystrophic Mice.
Circulation research Sep, 2017 | Pubmed ID: 28790199
Irisin protects mitochondria function during pulmonary ischemia/reperfusion injury.
Science translational medicine Nov, 2017 | Pubmed ID: 29187642
Zinc in Wound Healing Modulation.
Nutrients Dec, 2017 | Pubmed ID: 29295546
Comparative analysis of FKBP family protein: evaluation, structure, and function in mammals and Drosophila melanogaster.
BMC developmental biology 03, 2018 | Pubmed ID: 29587629
Quantum confined peptide assemblies with tunable visible to near-infrared spectral range.
Nature communications 08, 2018 | Pubmed ID: 30104564
MG 53 Protein Protects Aortic Valve Interstitial Cells From Membrane Injury and Fibrocalcific Remodeling.
Journal of the American Heart Association 02, 2019 | Pubmed ID: 30741589
MG53 promotes corneal wound healing and mitigates fibrotic remodeling in rodents.
Communications biology , 2019 | Pubmed ID: 30793049
MG53 attenuates lipopolysaccharide-induced neurotoxicity and neuroinflammation via inhibiting TLR4/NF-κB pathway in vitro and in vivo.
Progress in neuro-psychopharmacology & biological psychiatry 12, 2019 | Pubmed ID: 31260721
Sustained elevation of MG53 in the bloodstream increases tissue regenerative capacity without compromising metabolic function.
Nature communications 10, 2019 | Pubmed ID: 31604915
N-acetylcysteine prevents oxidized low-density lipoprotein-induced reduction of MG53 and enhances MG53 protective effect on bone marrow stem cells.
Journal of cellular and molecular medicine 01, 2020 | Pubmed ID: 31742908
The TRIM protein Mitsugumin 53 enhances survival and therapeutic efficacy of stem cells in murine traumatic brain injury.
Stem cell research & therapy 11, 2019 | Pubmed ID: 31779687
TRIC-A Channel Maintains Store Calcium Handling by Interacting With Type 2 Ryanodine Receptor in Cardiac Muscle.
Circulation research 02, 2020 | Pubmed ID: 31805819
MG53 Does Not Manifest the Development of Diabetes in Mice.
Diabetes 05, 2020 | Pubmed ID: 32139593
MG53 suppresses interferon-β and inflammation via regulation of ryanodine receptor-mediated intracellular calcium signaling.
Nature communications 07, 2020 | Pubmed ID: 32681036
Peptidylarginine Deiminases 2 Mediates Caspase-1-Associated Lethality in Pseudomonas aeruginosa Pneumonia-Induced Sepsis.
The Journal of infectious diseases Mar, 2021 | Pubmed ID: 32729925
Recombinant MG53 Protein Protects Mice from Lethal Influenza Virus Infection.
American journal of respiratory and critical care medicine 01, 2021 | Pubmed ID: 33031705
MG53, A Tissue Repair Protein with Broad Applications in Regenerative Medicine.
Cells 01, 2021 | Pubmed ID: 33440658
TRIC-A regulates intracellular Ca homeostasis in cardiomyocytes.
Pflugers Archiv : European journal of physiology 03, 2021 | Pubmed ID: 33474637
MG53 as a Novel Therapeutic Protein to Treat Acute Lung Injury.
Military medicine 01, 2021 | Pubmed ID: 33499468
Muscle multiorgan crosstalk with MG53 as a myokine for tissue repair and regeneration.
Current opinion in pharmacology 08, 2021 | Pubmed ID: 34052525
Efficient precise in vivo base editing in adult dystrophic mice.
Nature communications 06, 2021 | Pubmed ID: 34140489
MG53 suppresses tumor progression and stress granule formation by modulating G3BP2 activity in non-small cell lung cancer.
Molecular cancer 09, 2021 | Pubmed ID: 34521423
Correction to: The TRIM protein Mitsugumin 53 enhances survival and therapeutic efficacy of stem cells in murine traumatic brain injury.
Stem cell research & therapy Sep, 2021 | Pubmed ID: 34593038
Ki Ho Park1,
Noah Weisleder2,
Jingsong Zhou3,
Kristyn Gumpper1,
Xinyu Zhou1,
Pu Duann4,
Jianjie Ma1,
Pei-Hui Lin1
1Department of Surgery, Davis Heart and Lung Research Institute, The Ohio State University Wexner Medical Center,
2Department of Physiology and Cell Biology, Davis Heart and Lung Research Institute, The Ohio State University Wexner Medical Center,
3Department of Molecular Biophysics and Physiology, Rush University Medical Center,
4Department of Internal Medicine, Davis Heart and Lung Research Institute, The Ohio State University Wexner Medical Center
Wei Zhang*,1,
Xinjuan Lei*,1,
Xin Zhou*,2,3,
Boling He1,
Liqin Xiao1,
Huimin Yue1,
Shulin Wang1,
Yuting Sun1,
Yajun Wu1,
Liyang Wang1,4,
George Ghartey-Kwansah1,
Odell D. Jones5,
Joseph L. Bryant6,
MengMeng Xu7,
Jianjie Ma3,
Xuehon Xu1
1National Engineering Laboratory for Resource Development of Endangered Crude Drugs in Northwest of China/CGDB, Shaanxi Normal University College of Life Sciences,
2Shaanxi Key Laboratory of Ischemic Cardiovascular Disease, Shaanxi Key Laboratory of Brain disorders, Institute of Basic & Translational Medicine, Xi'an Medical University,
3, Ohio State University College of Medicine,
4Hematology-Oncology Division, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School,
5, University of Pennsylvania ULAR,
6, University of Maryland School of Medicine,
7, Columbia University Medical Center
Yong Gyu Lee1,2,
Jung-Lye Kim1,2,
Andre F. Palmer3,
Brenda F. Reader4,
Jianjie Ma1,
Sylvester M. Black2,4,
Bryan A. Whitson1,2
1Department of Surgery Division of Cardiac Surgery, The Ohio State University Wexner Medical Center,
2The Collaboration for Organ Perfusion, Protection, Engineering and Regeneration (COPPER) Laboratory, The Ohio State University College of Medicine,
3William G. Lowrie Department of Chemical and Biomolecular Engineering, College of Engineering, The Ohio State University,
4Comprehensive Transplant Center, The Ohio State University Wexner Medical Center
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