Oxford Centre for Diabetes,
Endocrinology and Metabolism,
Oxford Centre for Diabetes, Endocrinology and Metabolism
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Identification of the PIP2-binding site on Kir6.2 by molecular modelling and functional analysis.
The EMBO journal Aug, 2007 | Pubmed ID: 17673911
Insulin storage and glucose homeostasis in mice null for the granule zinc transporter ZnT8 and studies of the type 2 diabetes-associated variants.
Diabetes Sep, 2009 | Pubmed ID: 19542200
Incretin-modulated beta cell energetics in intact islets of Langerhans.
Molecular endocrinology (Baltimore, Md.) Jun, 2014 | Pubmed ID: 24766140
Use of genetically encoded sensors to monitor cytosolic ATP/ADP ratio in living cells.
Methods in enzymology , 2014 | Pubmed ID: 24862272
GLP-1 stimulates insulin secretion by PKC-dependent TRPM4 and TRPM5 activation.
The Journal of clinical investigation Dec, 2015 | Pubmed ID: 26571400
Dramatis Personae in β-Cell Mass Regulation: Enter SerpinB1.
Cell metabolism Jan, 2016 | Pubmed ID: 26771113
Increased Expression of the Diabetes Gene SOX4 Reduces Insulin Secretion by Impaired Fusion Pore Expansion.
Diabetes 07, 2016 | Pubmed ID: 26993066
Angular Approach Scanning Ion Conductance Microscopy.
Biophysical journal 05, 2016 | Pubmed ID: 27224490
Fumarate Hydratase Deletion in Pancreatic β Cells Leads to Progressive Diabetes.
Cell reports Sep, 2017 | Pubmed ID: 28954230
AP2σ Mutations Impair Calcium-Sensing Receptor Trafficking and Signaling, and Show an Endosomal Pathway to Spatially Direct G-Protein Selectivity.
Cell reports 01, 2018 | Pubmed ID: 29420171
Adrenaline Stimulates Glucagon Secretion by Tpc2-Dependent Ca Mobilization From Acidic Stores in Pancreatic α-Cells.
Diabetes 06, 2018 | Pubmed ID: 29563152
Monitoring real-time hormone release kinetics via high-content 3-D imaging of compensatory endocytosis.
Lab on a chip 09, 2018 | Pubmed ID: 30083680
Dysregulation of Glucagon Secretion by Hyperglycemia-Induced Sodium-Dependent Reduction of ATP Production.
Cell metabolism 02, 2019 | Pubmed ID: 30415925
Electrophysiological properties of human beta-cell lines EndoC-βH1 and -βH2 conform with human beta-cells.
Scientific reports 11, 2018 | Pubmed ID: 30451893
Diabetes causes marked inhibition of mitochondrial metabolism in pancreatic β-cells.
Nature communications 06, 2019 | Pubmed ID: 31171772
1Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford,
2Lund University Diabetes Centre, Unit of Molecular Metabolism, Clinical Research Centre, Malmö University HospitalMalmö,
3Institute of Neuroscience of Physiology, Department of Physiology, Metabolic Research Unit, University of Göteborg,
4Oxford National Institute for Health Research, Biomedical Research Centre,
5Life and Medical Sciences, University of Hertfordshire
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