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Development of a simple, rapid, and robust intrathecal catheterization method in the rat.
Journal of neuroscience methods 03, 2017 | Pubmed ID: 28163066
Antisense oligonucleotides selectively suppress target RNA in nociceptive neurons of the pain system and can ameliorate mechanical pain.
Pain 01, 2018 | Pubmed ID: 28976422
Antisense suppression of glial fibrillary acidic protein as a treatment for Alexander disease.
Annals of neurology 01, 2018 | Pubmed ID: 29226998
Time-dependent, bidirectional, anti- and pro-spinal hyper-reflexia and muscle spasticity effect after chronic spinal glycine transporter 2 (GlyT2) oligonucleotide-induced downregulation.
Experimental neurology 07, 2018 | Pubmed ID: 29608917
A modular analysis of microglia gene expression, insights into the aged phenotype.
BMC genomics Feb, 2019 | Pubmed ID: 30819113
Antisense oligonucleotides extend survival of prion-infected mice.
JCI insight 07, 2019 | Pubmed ID: 31361599
Brain pharmacology of intrathecal antisense oligonucleotides revealed through multimodal imaging.
JCI insight Oct, 2019 | Pubmed ID: 31619586
Ionis Pharmaceuticals
Yi Chen*,1,
Curt Mazur*,2,
Yi Luo*,1,
Linhong Sun1,
Mingdi Zhang1,
Alex McCampbell1,
Giulio Srubek Tomassy1
1, Biogen, Inc.,
2, Ionis Pharmaceuticals
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