School of Medicine,
Collaborative Innovation Center for Biotherapy
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SOX2 promotes tumorigenesis and increases the anti-apoptotic property of human prostate cancer cell.
Journal of molecular cell biology Aug, 2011 | Pubmed ID: 21415100
Downregulation of transcription factor Oct4 induces an epithelial-to-mesenchymal transition via enhancement of Ca2+ influx in breast cancer cells.
Biochemical and biophysical research communications Aug, 2011 | Pubmed ID: 21798248
Activating transcription factor 4 increases chemotherapeutics resistance of human hepatocellular carcinoma.
Cancer biology & therapy Apr, 2012 | Pubmed ID: 22338651
Fra-1 promotes breast cancer chemosensitivity by driving cancer stem cells from dormancy.
Cancer research Jul, 2012 | Pubmed ID: 22586064
Loss of vitamin D receptor in chronic kidney disease: a potential mechanism linking inflammation to epithelial-to-mesenchymal transition.
American journal of physiology. Renal physiology Oct, 2012 | Pubmed ID: 22791341
Alginic acid-coated chitosan nanoparticles loaded with legumain DNA vaccine: effect against breast cancer in mice.
PloS one , 2013 | Pubmed ID: 23577091
Yes-associated protein (YAP) increases chemosensitivity of hepatocellular carcinoma cells by modulation of p53.
Cancer biology & therapy Jun, 2013 | Pubmed ID: 23760493
VDR status arbitrates the prometastatic effects of tumor-associated macrophages.
Molecular cancer research : MCR Aug, 2014 | Pubmed ID: 24821711
Legumain protease-activated TAT-liposome cargo for targeting tumours and their microenvironment.
Nature communications Jun, 2014 | Pubmed ID: 24969588
Overexpression of Oct4 suppresses the metastatic potential of breast cancer cells via Rnd1 downregulation.
Biochimica et biophysica acta Nov, 2014 | Pubmed ID: 25068817
Clinicopathologic significance of legumain overexpression in cancer: a systematic review and meta-analysis.
Scientific reports Nov, 2015 | Pubmed ID: 26607955
Polymeric Nanomedicine for Combined Gene/chemo-therapy Elicits Enhanced Tumor Suppression.
Molecular pharmaceutics Dec, 2015 | Pubmed ID: 26695934
Pigment epithelial-derived factor gene loaded novel COOH-PEG-PLGA-COOH nanoparticles promoted tumor suppression by systemic administration.
International journal of nanomedicine , 2016 | Pubmed ID: 26955272
JMJD3 promotes survival of diffuse large B-cell lymphoma subtypes via distinct mechanisms.
Oncotarget May, 2016 | Pubmed ID: 27102442
miR-200 family promotes podocyte differentiation through repression of RSAD2.
Scientific reports 06, 2016 | Pubmed ID: 27251424
M2 tumour-associated macrophages contribute to tumour progression via legumain remodelling the extracellular matrix in diffuse large B cell lymphoma.
Scientific reports 07, 2016 | Pubmed ID: 27464733
Promising Nanocarriers for PEDF Gene Targeting Delivery to Cervical Cancer Cells Mediated by the Over-expressing FRα.
Scientific reports 08, 2016 | Pubmed ID: 27576898
Combined Tumor- and Neovascular-"Dual Targeting" Gene/Chemo-Therapy Suppresses Tumor Growth and Angiogenesis.
ACS applied materials & interfaces Oct, 2016 | Pubmed ID: 27615739
JMJD3 suppresses stem cell-like characteristics in breast cancer cells by downregulation of Oct4 independently of its demethylase activity.
Oncotarget Mar, 2017 | Pubmed ID: 28423536
Legumain, an asparaginyl endopeptidase, mediates the effect of M2 macrophages on attenuating renal interstitial fibrosis in obstructive nephropathy.
Kidney international 07, 2018 | Pubmed ID: 29656902
A resolved discrepancy between multiplex PCR and multiplex ligation-dependent probe amplification by targeted next-generation sequencing discloses a novel partial exonic deletion in the Duchenne muscular dystrophy gene.
Journal of clinical laboratory analysis Oct, 2018 | Pubmed ID: 29802662
Deletion of asparagine endopeptidase reduces anxiety- and depressive-like behaviors and improves abilities of spatial cognition in mice.
Brain research bulletin 09, 2018 | Pubmed ID: 30030107
Macrophage Foam Cell-Targeting Immunization Attenuates Atherosclerosis.
Frontiers in immunology , 2018 | Pubmed ID: 30687328
Recent Progress on Liquid Biopsy Analysis using Surface-Enhanced Raman Spectroscopy.
Theranostics , 2019 | Pubmed ID: 30809289
Asparaginyl endopeptidase induces endothelial permeability and tumor metastasis via downregulating zonula occludens protein ZO-1.
Biochimica et biophysica acta. Molecular basis of disease 09, 2019 | Pubmed ID: 31096007
Alginate microspheres prepared by ionic crosslinking of pickering alginate emulsions.
Journal of biomaterials science. Polymer edition 08, 2019 | Pubmed ID: 31159667
Skipping of an exon with a nonsense mutation in the DMD gene is induced by the conversion of a splicing enhancer to a splicing silencer.
Human genetics Jul, 2019 | Pubmed ID: 31168774
Legumain acts on neuroinflammatory to affect CUS-induced cognitive impairment.
Behavioural brain research 12, 2019 | Pubmed ID: 31509774
Etchable SERS nanosensor for accurate pH and hydrogen peroxide sensing in living cells.
Chemical communications (Cambridge, England) Oct, 2019 | Pubmed ID: 31608348
Legumain-deficient macrophages promote senescence of tumor cells by sustaining JAK1/STAT1 activation.
Cancer letters 03, 2020 | Pubmed ID: 31857155
MGAT3-mediated glycosylation of tetraspanin CD82 at asparagine 157 suppresses ovarian cancer metastasis by inhibiting the integrin signaling pathway.
Theranostics , 2020 | Pubmed ID: 32483464
Low-dose salinomycin inhibits breast cancer metastasis by repolarizing tumor hijacked macrophages toward the M1 phenotype.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences Feb, 2021 | Pubmed ID: 33176191
Legumain promotes tubular ferroptosis by facilitating chaperone-mediated autophagy of GPX4 in AKI.
Cell death & disease Jan, 2021 | Pubmed ID: 33431801
Colorimetric analysis of extracellular vesicle surface proteins based on controlled growth of Au aptasensors.
The Analyst Feb, 2021 | Pubmed ID: 33528468
Size-Dependent Penetration of Gold Nanoprobes into Fixed Cells.
ACS omega Feb, 2021 | Pubmed ID: 33585758
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