Xiaoling Zhou
Stem Cell Research Center,
The Center for Reproductive Medicine,
Guangdong Provincial Key Laboratory of Infectious Diseases and Molecular Immunopathology
Shantou University Medical College
2007- Up to now, Stem Cell Research Center, Shantou University Medical College, Research Center for Reproductive Medicine, Guangdong Provincial Key Laboratory of Infectious Diseases and Molecular Immunopathology, Shantou University Medical College, Shantou 515041, People's Republic of China
2004-2007, Ocean University of China, Ph.D.
2010-2011 Yale Stem Cell Center, Visiting Scholar
2012-2013 Centre for Regenerative Medicince, the University of Edinburgh, Researcher
My research focuses on modeling liver biology using pluripotent stem cells (hESCs and hiPSCs) derived hepatocytes and applying this novel model to study liver diseases. I previously studied HBV pathology in hepatic and non-hepatic cells and investigated the virus-host interaction in hepatic and non-hepatic cells and setting up new model by stem cell technology.
Effects of hepatitis B virus S protein exposure on sperm membrane integrity and functions.
PloS one , 2012 | Pubmed ID: 22470450
Expression pattern of asialoglycoprotein receptor in human testis.
Cell and tissue research Jun, 2013 | Pubmed ID: 23604802
Modeling human liver biology using stem cell-derived hepatocytes.
International journal of molecular sciences Nov, 2013 | Pubmed ID: 24201130
Modulating innate immunity improves hepatitis C virus infection and replication in stem cell-derived hepatocytes.
Stem cell reports Jul, 2014 | Pubmed ID: 25068132
A rapid and efficient polyethylenimine-based transfection method to prepare lentiviral or retroviral vectors: useful for making iPS cells and transduction of primary cells.
Biotechnology letters Sep, 2016 | Pubmed ID: 27193760
An efficient rapid system for assaying HBx-mediated transactivation.
Biotechnology letters Jul, 2017 | Pubmed ID: 28386736
Optimized PEI-based Transfection Method for Transient Transfection and Lentiviral Production.
Current protocols in chemical biology Sep, 2017 | Pubmed ID: 28910855
Defined host factors support HBV infection in non-hepatic 293T cells.
Journal of cellular and molecular medicine Feb, 2020 | Pubmed ID: 31930674
The Interactions between HBV and the Innate Immunity of Hepatocytes.
Viruses Mar, 2020 | Pubmed ID: 32151000
Hepatitis B virus surface protein induces oxidative stress by increasing peroxides and inhibiting antioxidant defences in human spermatozoa.
Reproduction, fertility, and development Oct, 2020 | Pubmed ID: 32998796
Modeling Hepatitis B Virus Infection in Non-Hepatic 293T-NE-3NRs Cells
Xiaoyue Sun*,1,2,3,
Xiaoqiang Yang*,1,2,3,4,
Chui Zeng1,2,3,
Fayed Attia Koutb Megahed1,2,3,5,
Qi Zhou1,2,3,
Tingdang Liu1,2,3,
Waqas Iqbal1,2,3,
Pingnan Sun1,2,3,
Xiaoling Zhou1,2,3
1Stem Cell Research Center, Shantou University Medical College,
2The Center for Reproductive Medicine, Shantou University Medical College,
3Guangdong Provincial Key Laboratory of Infectious Diseases and Molecular Immunopathology, Shantou University Medical College,
4Medical Research Center, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University,
5Department of Nucleic Acid Researches, Genetic Engineering and Biotechnology Research Institute, General Autority - City of Scientific Researches and Technological Applications
An Efficient Method for Directed Hepatocyte-Like Cell Induction from Human Embryonic Stem Cells
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