Department of Biochemistry,
Institute of Chemistry,
Department of Biochemistry, Institute of Chemistry
Carla Columbano Oliveira is an Associate Professor in the Department of Biochemistry, Institute of Chemistry, University of São Paulo, SP, Brazil. She received her undergraduate with honors degree in Biological Sciences from State University of Londrina, a Master's degree in Genetics and Molecular Biology from Federal University of Rio Grande do Sul, a PhD in Molecular Biology - Gesellschaft für Biotechnologische Forshung, Braunschweig, Germany, and a post-doc at the University of Rochester, NY, USA. During Dr. Oliveira’s training she developed a keen focus on research that encompasses aspects of posttranscriptional control of gene expression, focosing on RNA processing and degradation, using budding yeast as a model organism.
In 1998, she was recruited as faculty at the Biochemstry Department of University of São Paulo, whe she studies pre-rRNA processing and pre-mRNA splicing in Saccharomyces cerevisiae.
Temperature-sensitive mutants of the exosome subunit Rrp43p show a deficiency in mRNA degradation and no longer interact with the exosome.
Nucleic acids research Oct, 2002 | Pubmed ID: 12364597
Nop53p, an essential nucleolar protein that interacts with Nop17p and Nip7p, is required for pre-rRNA processing in Saccharomyces cerevisiae.
The FEBS journal Sep, 2005 | Pubmed ID: 16128814
Cwc24p, a novel Saccharomyces cerevisiae nuclear ring finger protein, affects pre-snoRNA U3 splicing.
The Journal of biological chemistry Feb, 2008 | Pubmed ID: 17974558
Nop53p interacts with 5.8S rRNA co-transcriptionally, and regulates processing of pre-rRNA by the exosome.
The FEBS journal Aug, 2008 | Pubmed ID: 18631361
Sdo1p, the yeast orthologue of Shwachman-Bodian-Diamond syndrome protein, binds RNA and interacts with nuclear rRNA-processing factors.
Yeast (Chichester, England) May, 2009 | Pubmed ID: 19350533
Expression, purification and structural analysis of the Pyrococcus abyssi RNA binding protein PAB1135.
BMC research notes Apr, 2010 | Pubmed ID: 20380716
Identification of archaeal proteins that affect the exosome function in vitro.
BMC biochemistry May, 2010 | Pubmed ID: 20507607
Utp25p, a nucleolar Saccharomyces cerevisiae protein, interacts with U3 snoRNP subunits and affects processing of the 35S pre-rRNA.
The FEBS journal Jul, 2010 | Pubmed ID: 20528918
The essential nucleolar yeast protein Nop8p controls the exosome function during 60S ribosomal subunit maturation.
PloS one , 2011 | Pubmed ID: 21747919
The human nucleolar protein FTSJ3 associates with NIP7 and functions in pre-rRNA processing.
PloS one , 2011 | Pubmed ID: 22195017
Cwc24p is a general Saccharomyces cerevisiae splicing factor required for the stable U2 snRNP binding to primary transcripts.
PloS one , 2012 | Pubmed ID: 23029180
Proteomic analysis of yeast mutant RNA exosome complexes.
Journal of proteome research Dec, 2013 | Pubmed ID: 24237138
Nop17 is a key R2TP factor for the assembly and maturation of box C/D snoRNP complex.
BMC molecular biology Mar, 2015 | Pubmed ID: 25888478
Identification of karyopherins involved in the nuclear import of RNA exosome subunit Rrp6 in .
The Journal of biological chemistry 07, 2017 | Pubmed ID: 28539363
Human RNF113A participates of pre-mRNA splicing in vitro.
Journal of cellular biochemistry Dec, 2018 | Pubmed ID: 30506991
Differential expression of RNA exosome subunits in the amphibian Lithobates catesbeianus during reproductive and non-reproductive periods.
BMC research notes Jan, 2019 | Pubmed ID: 30665462
The ribosome assembly factor Nop53 controls association of the RNA exosome with pre-60S particles in yeast.
The Journal of biological chemistry 12, 2019 | Pubmed ID: 31662437
Effectiveness of Manual and Electrical Acupuncture for Chronic Non-specific Low Back Pain: A Randomized Controlled Trial.
Journal of acupuncture and meridian studies Jun, 2020 | Pubmed ID: 32224119
Nucleolar localization of the yeast RNA exosome subunit Rrp44 hints at early pre-rRNA processing as its main function.
The Journal of biological chemistry Aug, 2020 | Pubmed ID: 32554806
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