Lichen Zhang

The scaffolding function of the RLTPR protein explains its essential role for CD28 co-stimulation in mouse and human T cells.

PLCE1 Promotes Esophageal Cancer Cell Progression by Maintaining the Transcriptional Activity of Snail.

A point mutation in the extracellular domain of CD4 completely abolishes CD4 T cell development in C57BL/6 mouse.

SHARPIN stabilizes estrogen receptor α and promotes breast cancer cell proliferation.

Speed genome editing by transient CRISPR/Cas9 targeting and large DNA fragment deletion.

A severe atherosclerosis mouse model on the resistant NOD background.

Precise and Rapid Validation of Candidate Gene by Allele Specific Knockout With CRISPR/Cas9 in Wild Mice.

The three members of the Vav family proteins form complexes that concur to foam cell formation and atherosclerosis.

Quantitative interactomics in primary T cells unveils TCR signal diversification extent and dynamics.

Both JNK1 and JNK2 Are Indispensable for Sensitized Extracellular Matrix Mineralization in IKKβ-Deficient Osteoblasts.

Regulation of Hippo/YAP signaling and Esophageal Squamous Carcinoma progression by an E3 ubiquitin ligase PARK2.

Gfi1 and Zc3h12c orchestrate a negative feedback loop that inhibits NF-kB activation during inflammation in macrophages.

Loss of natural resistance to schistosome in T cell deficient rat.

An inducible model for specific neutrophil depletion by diphtheria toxin in mice.

Zdhhc2 Is Essential for Plasmacytoid Dendritic Cells Mediated Inflammatory Response in Psoriasis.

ARHGAP45 controls naïve T- and B-cell entry into lymph nodes and T-cell progenitor thymus seeding.