Sean S. Davies

Hydrolysis of bimatoprost (Lumigan) to its free acid by ocular tissue in vitro.

Isoketals: highly reactive gamma-ketoaldehydes formed from the H2-isoprostane pathway.

Localization of isoketal adducts in vivo using a single-chain antibody.

Quantification of dinor, dihydro metabolites of F2-isoprostanes in urine by liquid chromatography/tandem mass spectrometry.

Pyridoxamine analogues scavenge lipid-derived gamma-ketoaldehydes and protect against H2O2-mediated cytotoxicity.

Amitriptyline activates cardiac ryanodine channels and causes spontaneous sarcoplasmic reticulum calcium release.

Ischemia/reperfusion unveils impaired capacity of older adults to restrain oxidative insult.

F2-isoprostanes as an indicator and risk factor for coronary heart disease.

Treatment with a γ-ketoaldehyde scavenger prevents working memory deficits in hApoE4 mice.

Lipid peroxidation generates biologically active phospholipids including oxidatively N-modified phospholipids.

DC isoketal-modified proteins activate T cells and promote hypertension.

Immune activation caused by vascular oxidation promotes fibrosis and hypertension.

Effect of Drug Therapy on Net Cholesterol Efflux Capacity of High-Density Lipoprotein-Enriched Serum in Rheumatoid Arthritis.

Microbial metabolism of dietary components to bioactive metabolites: opportunities for new therapeutic interventions.

Accumulation of isolevuglandin-modified protein in normal and fibrotic lung.

Dendritic cells and isolevuglandins in immunity, inflammation, and hypertension.

Net cholesterol efflux capacity of HDL enriched serum and coronary atherosclerosis in rheumatoid arthritis.

Leptogenic effects of NAPE require activity of NAPE-hydrolyzing phospholipase D.

Modification by isolevuglandins, highly reactive γ-ketoaldehydes, deleteriously alters high-density lipoprotein structure and function.

Isolevuglandins and cardiovascular disease.

Simplified LC/MS assay for the measurement of isolevuglandin protein adducts in plasma and tissue samples.

Administration of N-Acyl-Phosphatidylethanolamine Expressing Bacteria to Low Density Lipoprotein Receptor Mice Improves Indices of Cardiometabolic Disease.

Two-week administration of engineered Escherichia coli establishes persistent resistance to diet-induced obesity even without antibiotic pre-treatment.

Arachidonic Acid Kills Staphylococcus aureus through a Lipid Peroxidation Mechanism.

Modified sites and functional consequences of 4-oxo-2-nonenal adducts in HDL that are elevated in familial hypercholesterolemia.

Symmetrically substituted dichlorophenes inhibit -acyl-phosphatidylethanolamine phospholipase D.

Progressively decreasing plasma high-density lipoprotein cholesterol levels preceding diagnosis of smoldering myeloma.

Pro-inflammatory HDL in women with obesity and nonalcoholic steatohepatitis.

Reactive Dicarbonyl Scavenging Effectively Reduces MPO-Mediated Oxidation of HDL and Restores PON1 Activity.

Engineering the gut microbiota to treat chronic diseases.

Sodium activates human monocytes via the NADPH oxidase and isolevuglandin formation.

Kidney injury-mediated disruption of intestinal lymphatics involves dicarbonyl-modified lipoproteins.