Mauricio J. Reginato
Department of Biochemistry and Molecular Biology
Drexel University College of Medicine
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ErbB2 requires integrin alpha5 for anoikis resistance via Src regulation of receptor activity in human mammary epithelial cells.
Journal of cell science Apr, 2010 | Pubmed ID: 20332114
Hypoxia suppression of Bim and Bmf blocks anoikis and luminal clearing during mammary morphogenesis.
Molecular biology of the cell Nov, 2010 | Pubmed ID: 20861305
Surviving without oxygen: hypoxia regulation of mammary morphogenesis and anoikis.
Cell cycle (Georgetown, Tex.) Jul, 2011 | Pubmed ID: 21670595
Constitutive K-RasG12D activation of ERK2 specifically regulates 3D invasion of human pancreatic cancer cells via MMP-1.
Molecular cancer research : MCR Feb, 2012 | Pubmed ID: 22160930
Critical role of O-Linked β-N-acetylglucosamine transferase in prostate cancer invasion, angiogenesis, and metastasis.
The Journal of biological chemistry Mar, 2012 | Pubmed ID: 22275356
ERK2-regulated TIMP1 induces hyperproliferation of K-Ras(G12D)-transformed pancreatic ductal cells.
Neoplasia (New York, N.Y.) Apr, 2013 | Pubmed ID: 23555182
The oncogene HER2/neu (ERBB2) requires the hypoxia-inducible factor HIF-1 for mammary tumor growth and anoikis resistance.
The Journal of biological chemistry May, 2013 | Pubmed ID: 23585570
Activated ERBB2/HER2 licenses sensitivity to apoptosis upon endoplasmic reticulum stress through a PERK-dependent pathway.
Cancer research Mar, 2014 | Pubmed ID: 24453000
Sticking to sugars at the metastatic site: sialyltransferase ST6GalNAc2 acts as a breast cancer metastasis suppressor.
Cancer discovery Mar, 2014 | Pubmed ID: 24596201
O-GlcNAcylation regulates cancer metabolism and survival stress signaling via regulation of the HIF-1 pathway.
Molecular cell Jun, 2014 | Pubmed ID: 24857547
Cancer metabolism: cross talk between signaling and O-GlcNAcylation.
Methods in molecular biology (Clifton, N.J.) , 2014 | Pubmed ID: 25030920
EMT Transition Alters Interstitial Fluid Flow-Induced Signaling in ERBB2-Positive Breast Cancer Cells.
Molecular cancer research : MCR Apr, 2015 | Pubmed ID: 25566992
Hypoxia/HIF1α induces lapatinib resistance in ERBB2-positive breast cancer cells via regulation of DUSP2.
Oncotarget Feb, 2015 | Pubmed ID: 25596742
mTOR/MYC Axis Regulates O-GlcNAc Transferase Expression and O-GlcNAcylation in Breast Cancer.
Molecular cancer research : MCR May, 2015 | Pubmed ID: 25636967
Emerging microtubule targets in glioma therapy.
Seminars in pediatric neurology Mar, 2015 | Pubmed ID: 25976261
Progress toward overcoming hypoxia-induced resistance to solid tumor therapy.
Cancer management and research , 2015 | Pubmed ID: 26316817
O-GlcNAcylation in Cancer Biology: Linking Metabolism and Signaling.
Journal of molecular biology 08, 2016 | Pubmed ID: 27343361
O-GlcNAcylation regulates breast cancer metastasis via SIRT1 modulation of FOXM1 pathway.
Oncogene 01, 2017 | Pubmed ID: 27345396
Proapoptotic protein Bim attenuates estrogen-enhanced survival in lymphangioleiomyomatosis.
JCI insight Nov, 2016 | Pubmed ID: 27882343
Nutrient sensor O-GlcNAc transferase controls cancer lipid metabolism via SREBP-1 regulation.
Oncogene 02, 2018 | Pubmed ID: 29059153
O-GlcNAcylation: key regulator of glycolytic pathways.
Journal of bioenergetics and biomembranes 06, 2018 | Pubmed ID: 29344764
Breast Cancer Brain Metastasis Response to Radiation After Microbubble Oxygen Delivery in a Murine Model.
Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine Dec, 2019 | Pubmed ID: 31124171
Fueling the fire: emerging role of the hexosamine biosynthetic pathway in cancer.
BMC biology 07, 2019 | Pubmed ID: 31272438
O-GlcNAc Transferase Regulates Cancer Stem-like Potential of Breast Cancer Cells.
Molecular cancer research : MCR 04, 2020 | Pubmed ID: 31974291
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