Jordan C. Langston
Department of Bioengineering
Temple University
Jordan C. Langston is currently a Ph.D. student in the Department of Bioengineering at Temple University in Philadelphia, PA. He received his undergraduate degree in chemistry with highest honors from Oakwood University in Huntsville, AL. He is a recipient of a NIH F31 NRSA fellowship and conducts research in the laboratory of Dr. Mohammad F. Kiani where he uses a synergistic combination of a novel microfluidic system employing human clinical material to address animal model limitations, proteomics analysis to study the evolution of cellular pathways during sepsis, an in silico model to study how neutrophil and endothelial inflammatory signaling and its associated regulatory mechanisms evolve during sepsis and machine learning to evaluate therapeutics and identify druggable targets for treating sepsis. His long-term goal is to not only better understand the mechanisms underlying the progression of sepsis but also develop a methodology to rationally design and screen therapeutics for this deadly disease.
Protein kinase C-delta inhibition protects blood-brain barrier from sepsis-induced vascular damage.
Journal of neuroinflammation Nov, 2018 | Pubmed ID: 30400800
The Role of Tyrosine Phosphorylation of Protein Kinase C Delta in Infection and Inflammation.
International journal of molecular sciences Mar, 2019 | Pubmed ID: 30917487
Mechanisms of radiation-induced endothelium damage: Emerging models and technologies.
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 05, 2021 | Pubmed ID: 33581220
Emerging Approaches to Understanding Microvascular Endothelial Heterogeneity: A Roadmap for Developing Anti-Inflammatory Therapeutics.
International journal of molecular sciences Jul, 2021 | Pubmed ID: 34360536
A Microphysiological System to Study Leukocyte-Endothelial Cell Interaction during Inflammation
Qingliang Yang1,
Jordan C. Langston2,
Yuan Tang3,
Balabhaskar Prabhakarpandian4,
Laurie E. Kilpatrick5,
Mohammad F. Kiani1,2,6
1Department of Mechanical Engineering, Temple University,
2Department of Bioengineering, Temple University,
3Department of Bioengineering, University of Toledo,
4Biomedical Technology, CFD Research Corporation,
5Center for Inflammation and Lung Research, Department of Microbiology, Immunology and Inflammation, Lewis Katz School of Medicine, Temple University,
6Department of Radiation Oncology, Lewis Katz School of Medicine, Temple University
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