Renal Section,
Department of Medicine
I entered medical school through a highly competitive matriculation process overseas. I successfully graduated as the top student, and in the continuum, toward my goal, I embarked on the first-ranked integrated five-year general and vascular surgery residency program, where I graduated with the highest honor in the national board exam and research.
Consequently, I started in the top-ranked pediatric surgery subspecialty clinical and research program. I led the first global gastrointestinal birth defect registry in collaboration with king’s college, London, England. The work was published in The Lancet(Global PaedSurg Research Collaboration. Lancet. 2021 Jul 24;398(10297):325-339. doi: 10.1016/S0140-6736(21)00767-4. Epub 2021 Jul 13. PMID: 34270932; PMCID: PMC8314066)
Considering my salient achievements as the youngest double board-certified surgeon in the country and grant applicant, I won the travel award as a visiting scholar at the University of Alberta, Edmonton, Canada, in June 2019. Consequently, I joined the department of renal and vascular research at Boston University in October 2019 and subsequently was promoted to the research scientist position in February 2021. According to my work in vascular research, I was granted a strategically focused research fellowship by American Heart Association in July 2021 to continue my work at Boston Medical Center.
Since I joined Boston University in 2019, I have contributed to the publication of five seminal papers and more accepted for publications, 1. Lotfollahzadeh S, Lo D, York EA, et al. Pharmacologic Manipulation of Late SV40 Factor Suppresses Wnt Signaling and Inhibits Growth of Allogeneic and Syngeneic Colon Cancer Xenografts [published online ahead of print, 2022 Jun 13]. Am J Pathol. 2022; S0002-9440(22)00170-5. 2. (Arinze et al., J Clin Invest. 2022; 3. Walker et al., J Am Soc Nephrol. 2021; 4. Amraei R et al., Proc Natl Acad Sci U S A. 2022). 5. Edward Hartsough et al. iscence, July 2022, PRMT4 Mediated Arginine Methylation Promotes Tyrosine Phosphorylation of VEGFR-2 and Regulates Filopodia Protrusions
Moreover, according to my passion for innovative animal models, I have developed a novel rodent model to optimize peritoneal catheters, which has been recently published in the Journal of Visual Experiments. Additionally, I took the lead in collaborative research work with the department of biomedical engineering at Boston University to optimize and validate the application of animal models for spectroscopy in renal fibrosis.
Furthermore, I have cultivated my knowledge background in Surgery and contributed as the director and managing editor for continuous medical education to make the dream of available global education for medical students and medical professionals come true.
The effects of botulinum toxin injection on urodynamic changes in pediatric population with neurospastic bladder: First trial in Iran.
Journal of pediatric surgery Nov, 2020 | Pubmed ID: 32019705
Indoleamine 2,3-dioxygenase-1, a Novel Therapeutic Target for Post-Vascular Injury Thrombosis in CKD.
Journal of the American Society of Nephrology : JASN 11, 2021 | Pubmed ID: 34716244
Tryptophan metabolites suppress the Wnt pathway and promote adverse limb events in chronic kidney disease.
The Journal of clinical investigation 01, 2022 | Pubmed ID: 34752422
Extracellular vimentin is an attachment factor that facilitates SARS-CoV-2 entry into human endothelial cells.
Proceedings of the National Academy of Sciences of the United States of America 02, 2022 | Pubmed ID: 35078919
Pharmacologic Manipulation of Late SV40 Factor Suppresses Wnt Signaling and Inhibits Growth of Allogeneic and Syngeneic Colon Cancer Xenografts.
The American journal of pathology Jun, 2022 | Pubmed ID: 35710032
Calreticulin Regulates SARS-CoV-2 Spike Protein Turnover and Modulates SARS-CoV-2 Infectivity.
Cells Nov, 2023 | Pubmed ID: 38067122
Saran Lotfollahzadeh1,
Mengwei Zhang1,
Marc Arthur Napoleon1,
Wenqing Yin1,
Josephine Orrick1,
Nagla Elzind1,
Austin Morrissey1,
Isaac E. Sellinger1,
Lauren D. Stern1,
Mostafa Belghasem2,
Jean M. Francis1,
Vipul C. Chitalia1,3,4
1Renal Section, Department of Medicine, Boston University Aram V. Chobanian & Edward Avedisian School of Medicine,
2Department of Biomedical Science, Kaiser Permanente Bernard J. Tyson School of Medicine,
3, Veterans Affairs Boston Healthcare System,
4Institute of Medical Engineering and Sciences, Massachusetts Institute of Technology
Saran Lotfollahzadeh1,
Xiaosheng Yang1,
David Jasen Wu Wong1,
Jingyan Han2,
Francesca Seta2,
Suvranu Ganguli3,
Asha Jose1,
Katya Ravid4,5,
Vipul C. Chitalia1,6,7,8
1Renal Section, Department of Medicine, Chobanian and Avedisian School of Medicine, Boston University,
2Vascular Biology Section, Department of Medicine, Chobanian and Avedisian School of Medicine, Boston University,
3Division of Interventional Radiology, Department of Radiology, Chobanian and Avedisian School of Medicine, Boston University,
4Department of Medicine, Whitaker Cardiovascular Institute, Chobanian and Avedisian School of Medicine, Boston University,
5Department of Biochemistry and Cell Biology, Chobanian and Avedisian School of Medicine, Boston University,
6, Veterans Affairs Boston Healthcare System,
7Institute of Medical Engineering and Sciences, Massachusetts Institute of Technology,
8Center of Cross-Organ Vascular Pathology, Department of Medicine, Chobanian and Avedisian School of Medicine, Boston University
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