Isaac grew up in Los Angeles, and earned his B.A. in Molecular and Cell Biology from the University of California Berkeley in 2010. He completed his doctoral work in 2017 at the Massachusetts Institute of Technology under the supervision of Dr. Peter Reddien. There, he studied the regeneration of an adult tissue organizer and the patterning of stem cell lineages in planarians. He joined the Goessling lab in June 2017 as a postdoctoral fellow. Isaac is interested using single-cell sequencing and genetic approaches to studying liver regeneration in zebrafish. His current projects are supported by National Institute on Alcohol Abuse and Alcoholism (NIAAA).