Marcela Brissova

Assessment of insulin secretion in the mouse.

A fall in portal vein insulin does not cause the alpha-cell response to mild, non-insulin-induced hypoglycemia in conscious dogs.

Intraislet endothelial cells contribute to revascularization of transplanted pancreatic islets.

H-Ras, R-Ras, and TC21 differentially regulate ureteric bud cell branching morphogenesis.

Polymer scaffolds as synthetic microenvironments for extrahepatic islet transplantation.

Molecular imaging of vascular endothelial growth factor receptor 2 expression using targeted contrast-enhanced high-frequency ultrasonography.

Enhanced expression of VEGF-A in β cells increases endothelial cell number but impairs islet morphogenesis and β cell proliferation.

Pancreatic islet vasculature adapts to insulin resistance through dilation and not angiogenesis.

Vascular endothelial growth factor-a and islet vascularization are necessary in developing, but not adult, pancreatic islets.

Islet microenvironment, modulated by vascular endothelial growth factor-A signaling, promotes β cell regeneration.

Pancreas development in humans.

Automated quantification of pancreatic β-cell mass.

Human islet preparations distributed for research exhibit a variety of insulin-secretory profiles.

Thiobenzothiazole-modified Hydrocortisones Display Anti-inflammatory Activity with Reduced Impact on Islet β-Cell Function.

Human Islets Have Fewer Blood Vessels than Mouse Islets and the Density of Islet Vascular Structures Is Increased in Type 2 Diabetes.

Microtubules Negatively Regulate Insulin Secretion in Pancreatic β Cells.

Inactivating the permanent neonatal diabetes gene Mnx1 switches insulin-producing β-cells to a δ-like fate and reveals a facultative proliferative capacity in aged β-cells.

Development of a reliable automated screening system to identify small molecules and biologics that promote human β-cell regeneration.

Analysis of self-antigen specificity of islet-infiltrating T cells from human donors with type 1 diabetes.

Glycoprotein 2 is a specific cell surface marker of human pancreatic progenitors.

Mouse pancreatic islet macrophages use locally released ATP to monitor beta cell activity.

α Cell Function and Gene Expression Are Compromised in Type 1 Diabetes.

Cystic fibrosis-related diabetes is caused by islet loss and inflammation.

β-Cell DNA Damage Response Promotes Islet Inflammation in Type 1 Diabetes.

Examining How the MAFB Transcription Factor Affects Islet β-Cell Function Postnatally.

Ectonucleoside Triphosphate Diphosphohydrolase-3 Antibody Targets Adult Human Pancreatic β Cells for In Vitro and In Vivo Analysis.

Human islets expressing HNF1A variant have defective β cell transcriptional regulatory networks.

HLA Class II Antigen Processing and Presentation Pathway Components Demonstrated by Transcriptome and Protein Analyses of Islet β-Cells From Donors With Type 1 Diabetes.

Imaging mass spectrometry enables molecular profiling of mouse and human pancreatic tissue.

The Integrated Islet Distribution Program answers the call for improved human islet phenotyping and reporting of human islet characteristics in research articles.

The Integrated Islet Distribution Program Answers the Call for Improved Human Islet Phenotyping and Reporting of Human Islet Characteristics in Research Articles.

Modeling Monogenic Diabetes using Human ESCs Reveals Developmental and Metabolic Deficiencies Caused by Mutations in HNF1A.

Integrated human pseudoislet system and microfluidic platform demonstrate differences in GPCR signaling in islet cells.

Decreased pancreatic acinar cell number in type 1 diabetes.

SARS-CoV-2 Cell Entry Factors ACE2 and TMPRSS2 Are Expressed in the Microvasculature and Ducts of Human Pancreas but Are Not Enriched in β Cells.

Pancreatlas: Applying an Adaptable Framework to Map the Human Pancreas in Health and Disease.

Dopamine regulates pancreatic glucagon and insulin secretion via adrenergic and dopaminergic receptors.

Coordinated interactions between endothelial cells and macrophages in the islet microenvironment promote β cell regeneration.

The Human Islet: Mini-Organ With Mega-Impact.

Combinatorial transcription factor profiles predict mature and functional human islet α and β cells.

Microvessels enhance vascularization and function of transplanted insulin-producing cells.

Integrated Analysis of the Pancreas and Islets Reveals Unexpected Findings in Human Male With Type 1 Diabetes.

Images From the Exeter Archival Diabetes Biobank Now Accessible via Pancreatlas.

Human pancreatic capillaries and nerve fibers persist in type 1 diabetes despite beta cell loss.

The human α cell in health and disease.

Exocrine pancreas in type 1 and type 2 diabetes: different patterns of fibrosis, metaplasia, angiopathy, and adiposity.