Sergii Afonin has not added Biography.
If you are Sergii Afonin and would like to personalize this page please email our Author Liaison for assistance.
Synthesis of trifluoromethyl-substituted proline analogues as 19F NMR labels for peptides in the polyproline II conformation.
Angewandte Chemie (International ed. in English) , 2008 | Pubmed ID: 18576439
Conformation and membrane orientation of amphiphilic helical peptides by oriented circular dichroism.
Biophysical journal Oct, 2008 | Pubmed ID: 18621832
Temperature-dependent transmembrane insertion of the amphiphilic peptide PGLa in lipid bilayers observed by solid state 19F NMR spectroscopy.
Journal of the American Chemical Society Dec, 2008 | Pubmed ID: 19049452
Using a sterically restrictive amino acid as a 19F NMR label to monitor and to control peptide aggregation in membranes.
Journal of the American Chemical Society Dec, 2008 | Pubmed ID: 19554688
Chemical labeling strategy with (R)- and (S)-trifluoromethylalanine for solid state 19F NMR analysis of peptaibols in membranes.
Journal of the American Chemical Society Nov, 2009 | Pubmed ID: 19827760
Dynamic transitions of membrane-active peptides.
Methods in molecular biology (Clifton, N.J.) , 2010 | Pubmed ID: 20094866
19F NMR analysis of the antimicrobial peptide PGLa bound to native cell membranes from bacterial protoplasts and human erythrocytes.
Journal of the American Chemical Society Jul, 2010 | Pubmed ID: 20550126
Structural role of the conserved cysteines in the dimerization of the viral transmembrane oncoprotein E5.
Biophysical journal Sep, 2010 | Pubmed ID: 20858420
Special issue on membrane-active peptides.
European biophysics journal : EBJ Apr, 2011 | Pubmed ID: 21286705
Solid-state (19)F-NMR of peptides in native membranes.
Topics in current chemistry , 2012 | Pubmed ID: 21598096
Alignment of druglike compounds in lipid bilayers analyzed by solid-state (19)F-NMR and molecular dynamics, based on dipolar couplings of adjacent CF3 groups.
The journal of physical chemistry. B Apr, 2012 | Pubmed ID: 22439912
Hydrophobic matching controls the tilt and stability of the dimeric platelet-derived growth factor receptor (PDGFR) β transmembrane segment.
The Journal of biological chemistry Jul, 2012 | Pubmed ID: 22619173
Antimicrobial Peptides can Enhance the Risk of Persistent Infections.
Frontiers in immunology , 2012 | Pubmed ID: 22870073
Structure analysis of the membrane-bound PhoD signal peptide of the Tat translocase shows an N-terminal amphiphilic helix.
Biochimica et biophysica acta Dec, 2012 | Pubmed ID: 22960285
Incorporation of cis- and trans-4,5-difluoromethanoprolines into polypeptides.
Organic letters Oct, 2012 | Pubmed ID: 23020292
Solid State NMR Structure Analysis of the Antimicrobial Peptide Gramicidin S in Lipid Membranes: Concentration-Dependent Re-alignment and Self-Assembly as a β-Barrel.
Topics in current chemistry , 2008 | Pubmed ID: 23605461
Stereochemical effects on the aggregation and biological properties of the fibril-forming peptide [KIGAKI]3 in membranes.
Physical chemistry chemical physics : PCCP Jun, 2013 | Pubmed ID: 23652359
Controlling biological activity with light: diarylethene-containing cyclic peptidomimetics.
Angewandte Chemie (International ed. in English) Mar, 2014 | Pubmed ID: 24554486
(19)F NMR screening of unrelated antimicrobial peptides shows that membrane interactions are largely governed by lipids.
Biochimica et biophysica acta Sep, 2014 | Pubmed ID: 24699372
Structure analysis and conformational transitions of the cell penetrating peptide transportan 10 in the membrane-bound state.
PloS one , 2014 | Pubmed ID: 24937132
Control and role of pH in peptide-lipid interactions in oriented membrane samples.
Biochimica et biophysica acta Mar, 2015 | Pubmed ID: 25511586
Action of the multifunctional peptide BP100 on native biomembranes examined by solid-state NMR.
Journal of biomolecular NMR Apr, 2015 | Pubmed ID: 25616492
γ-(S)-Trifluoromethyl proline: evaluation as a structural substitute of proline for solid state (19)F-NMR peptide studies.
Organic & biomolecular chemistry Mar, 2015 | Pubmed ID: 25703116
Fermentation and Cost-Effective 13C/15N Labeling of the Nonribosomal Peptide Gramicidin S for Nuclear Magnetic Resonance Structure Analysis.
Applied and environmental microbiology Jun, 2015 | Pubmed ID: 25795666
Direct Photocontrol of Peptidomimetics: An Alternative to Oxygen-Dependent Photodynamic Cancer Therapy.
Angewandte Chemie (International ed. in English) Apr, 2016 | Pubmed ID: 27028784
Does a methionine-to-norleucine substitution in PGLa influence peptide-membrane interactions?
Biochimica et biophysica acta Sep, 2016 | Pubmed ID: 27267703
Membrane Thinning and Thickening Induced by Membrane-Active Amphipathic Peptides.
Frontiers in cell and developmental biology , 2016 | Pubmed ID: 27595096
Therapeutic Potential of Gramicidin S in the Treatment of Root Canal Infections.
Pharmaceuticals (Basel, Switzerland) Sep, 2016 | Pubmed ID: 27618065
Design, Synthesis, and Application of an Optimized Monofluorinated Aliphatic Label for Peptide Studies by Solid-State F NMR Spectroscopy.
Angewandte Chemie (International ed. in English) Nov, 2016 | Pubmed ID: 27706889
Delivering Structural Information on the Polar Face of Membrane-Active Peptides: F-NMR Labels with a Cationic Side Chain.
Angewandte Chemie (International ed. in English) Nov, 2016 | Pubmed ID: 27761988
Coding and decoding libraries of sequence-defined functional copolymers synthesized via photoligation.
Nature communications Nov, 2016 | Pubmed ID: 27901024
Orientation and Location of the Cyclotide Kalata B1 in Lipid Bilayers Revealed by Solid-State NMR.
Biophysical journal Feb, 2017 | Pubmed ID: 28256223
Antimicrobial peptide gramicidin S is accumulated in granules of producer cells for storage of bacterial phosphagens.
Scientific reports Mar, 2017 | Pubmed ID: 28295017
Diphytanoyl lipids as model systems for studying membrane-active peptides.
Biochimica et biophysica acta. Biomembranes Oct, 2017 | Pubmed ID: 28587828
Loosening of Lipid Packing Promotes Oligoarginine Entry into Cells.
Angewandte Chemie (International ed. in English) Jun, 2017 | Pubmed ID: 28597524
Conformational Plasticity of the Cell-Penetrating Peptide SAP As Revealed by Solid-State F-NMR and Circular Dichroism Spectroscopies.
The journal of physical chemistry. B Jul, 2017 | Pubmed ID: 28608690
Structural Behavior of the Peptaibol Harzianin HK VI in a DMPC Bilayer: Insights from MD Simulations.
Biophysical journal Jun, 2017 | Pubmed ID: 28636916
Lactam-Stapled Cell-Penetrating Peptides: Cell Uptake and Membrane Binding Properties.
Journal of medicinal chemistry Oct, 2017 | Pubmed ID: 28921993
Flexibility vs rigidity of amphipathic peptide conjugates when interacting with lipid bilayers.
Biochimica et biophysica acta. Biomembranes Dec, 2017 | Pubmed ID: 28958778
Orthogonal F-Labeling for Solid-State NMR Spectroscopy Reveals the Conformation and Orientation of Short Peptaibols in Membranes.
Chemistry (Weinheim an der Bergstrasse, Germany) Mar, 2018 | Pubmed ID: 29323432
Efficiently Photocontrollable or Not? Biological Activity of Photoisomerizable Diarylethenes.
Chemistry (Weinheim an der Bergstrasse, Germany) Aug, 2018 | Pubmed ID: 29633378
Structure-Activity Relationships of Photoswitchable Diarylethene-Based β-Hairpin Peptides as Membranolytic Antimicrobial and Anticancer Agents.
Journal of medicinal chemistry Dec, 2018 | Pubmed ID: 30452249
Inhibition of Pseudomonas aeruginosa biofilm formation and expression of virulence genes by selective epimerization in the peptide Esculentin-1a(1-21)NH.
The FEBS journal Oct, 2019 | Pubmed ID: 31144441
Supreme activity of gramicidin S against resistant, persistent and biofilm cells of staphylococci and enterococci.
Scientific reports Nov, 2019 | Pubmed ID: 31784584
Light-controllable dithienylethene-modified cyclic peptides: photoswitching the in vivo toxicity in zebrafish embryos.
Beilstein journal of organic chemistry , 2020 | Pubmed ID: 31976015
Nanomolar Synthesis in Droplet Microarrays with UV-Triggered On-Chip Cell Screening.
Small (Weinheim an der Bergstrasse, Germany) Mar, 2020 | Pubmed ID: 31985878
Enhancing the activity of membrane remodeling epsin-peptide by trimerization.
Bioorganic & medicinal chemistry letters Jun, 2020 | Pubmed ID: 32317210
Diarylethene moiety as an enthalpy-entropy switch: photoisomerizable stapled peptides for modulating p53/MDM2 interaction.
Organic & biomolecular chemistry Jul, 2020 | Pubmed ID: 32390036
Structural and functional characterization of the pore-forming domain of pinholin S68.
Proceedings of the National Academy of Sciences of the United States of America Nov, 2020 | Pubmed ID: 33154156
TAT-RasGAP kills cells by targeting inner-leaflet-enriched phospholipids.
Proceedings of the National Academy of Sciences of the United States of America Dec, 2020 | Pubmed ID: 33257567
Behavior of the Antibacterial Peptide Cyclo[RRRWFW], Explored Using a 3-Hydroxychromone-Derived Fluorescent Amino Acid.
Frontiers in chemistry , 2021 | Pubmed ID: 34262894
Diarylethene-Based Photoswitchable Inhibitors of Serine Proteases.
Angewandte Chemie (International ed. in English) Sep, 2021 | Pubmed ID: 34268844
Probing and Manipulating the Lateral Pressure Profile in Lipid Bilayers Using Membrane-Active Peptides-A Solid-State F NMR Study.
International journal of molecular sciences Apr, 2022 | Pubmed ID: 35562938
Towards in vivo photomediated delivery of anticancer peptides: Insights from pharmacokinetic and -dynamic data.
Journal of photochemistry and photobiology. B, Biology Aug, 2022 | Pubmed ID: 35660309
Highly Fluorinated Peptide Probes with Enhanced In Vivo Stability for F-MRI.
Small (Weinheim an der Bergstrasse, Germany) Oct, 2022 | Pubmed ID: 36074982
Length matters: Functional flip of the short TatA transmembrane helix.
Biophysical journal Jun, 2023 | Pubmed ID: 36523158
Structural Dissection of Epsin-1 N-Terminal Helical Peptide: The Role of Hydrophobic Residues in Modulating Membrane Curvature.
Chemistry (Weinheim an der Bergstrasse, Germany) May, 2023 | Pubmed ID: 36878866
关于 JoVE
版权所属 © 2024 MyJoVE 公司版权所有,本公司不涉及任何医疗业务和医疗服务。