Jennifer L. Gommerman

The LIGHT and DARC sides of herpesvirus entry mediator.

AID mutates a non-immunoglobulin transgene independent of chromosomal position.

LIGHT is dispensable for CD4+ and CD8+ T cell and antibody responses to influenza A virus in mice.

BAFF induces a hyper-IgA syndrome in the intestinal lamina propria concomitant with IgA deposition in the kidney independent of LIGHT.

The lymphotoxin pathway: beyond lymph node development.

Expression of lymphotoxin-alphabeta on antigen-specific T cells is required for DC function.

ICOS, CD40, and lymphotoxin beta receptors signal sequentially and interdependently to initiate a germinal center reaction.

Nod2-dependent Th2 polarization of antigen-specific immunity.

AID constrains germinal center size by rendering B cells susceptible to apoptosis.

Dynamic accumulation of plasmacytoid dendritic cells in lymph nodes is regulated by interferon-beta.

Differential requirement of MALT1 for BAFF-induced outcomes in B cell subsets.

Substrain differences reveal novel disease-modifying gene candidates that alter the clinical course of a rodent model of multiple sclerosis.

Cytokine/stromal cell networks and lymphoid tissue environments.

The lymphotoxin pathway as a novel regulator of dendritic cell function.

LTβR signaling in dendritic cells induces a type I IFN response that is required for optimal clonal expansion of CD8+ T cells.

Mice overexpressing BAFF develop a commensal flora-dependent, IgA-associated nephropathy.

LTβR and CD40: working together in dendritic cells to optimize immune responses.

Notch2 receptor signaling controls functional differentiation of dendritic cells in the spleen and intestine.

Acquisition of a multifunctional IgA+ plasma cell phenotype in the gut.

Unusual timing of CD127 expression by mouse uterine natural killer cells.

Fine-tuning of dendritic cell biology by the TNF superfamily.

Homeodomain-interacting protein kinase (HIPK)-1 is required for splenic B cell homeostasis and optimal T-independent type 2 humoral response.

Lymphotoxin-sensitive microenvironments in homeostasis and inflammation.

A sphingosine-1-phosphate receptor 1-directed agonist reduces central nervous system inflammation in a plasmacytoid dendritic cell-dependent manner.

Secondary B cell receptor diversification is necessary for T cell mediated neuro-inflammation during experimental autoimmune encephalomyelitis.

The Regulation of Immune Responses by DC Derived Type I IFN.

Notch2-dependent classical dendritic cells orchestrate intestinal immunity to attaching-and-effacing bacterial pathogens.

AID-expressing germinal center B cells cluster normally within lymph node follicles in the absence of FDC-M1+ CD35+ follicular dendritic cells but dissipate prematurely.

AID and caspase 8 shape the germinal center response through apoptosis.

The Lymphotoxin Network: orchestrating a type I interferon response to optimize adaptive immunity.

The 14th International TNF Conference, Québec City, Canada - Des Progrės Récents aux Défis Futurs (Recent Advances toward Future Challenges).

HIV acquisition is associated with increased antimicrobial peptides and reduced HIV neutralizing IgA in the foreskin prepuce of uncircumcised men.

Re-thinking the functions of IgA(+) plasma cells.

Asthma, type 1 and type 2 diabetes mellitus, and inflammatory bowel disease amongst South Asian immigrants to Canada and their children: a population-based cohort study.

B cells in MS: Why, where and how?

A Lymphotoxin/Type I IFN Axis Programs CD8+ T Cells To Infiltrate a Self-Tissue and Propagate Immunopathology.

Proinflammatory GM-CSF-producing B cells in multiple sclerosis and B cell depletion therapy.

Hematopoietic LTβR deficiency results in skewed T cell cytokine profiles during a mucosal viral infection.

Integration of Th17- and Lymphotoxin-Derived Signals Initiates Meningeal-Resident Stromal Cell Remodeling to Propagate Neuroinflammation.

B Cells in the Multiple Sclerosis Central Nervous System: Trafficking and Contribution to CNS-Compartmentalized Inflammation.

Cytokine-Defined B Cell Responses as Therapeutic Targets in Multiple Sclerosis.

Meningeal Tertiary Lymphoid Tissues and Multiple Sclerosis: A Gathering Place for Diverse Types of Immune Cells during CNS Autoimmunity.

The SAGA Deubiquitination Module Promotes DNA Repair and Class Switch Recombination through ATM and DNAPK-Mediated γH2AX Formation.

Stromal Cell Niches in the Inflamed Central Nervous System.

Antibody-Independent Function of Human B Cells Contributes to Antifungal T Cell Responses.

Three-Dimensional Imaging of Transparent Tissues via Metal Nanoparticle Labeling.

The H2B deubiquitinase Usp22 promotes antibody class switch recombination by facilitating non-homologous end joining.

Isotype-Switched Autoantibodies Are Necessary To Facilitate Central Nervous System Autoimmune Disease in and Mice.

Generational Patterns of Asthma Incidence among Immigrants to Canada over Two Decades. A Population-based Cohort Study.

Recirculating Intestinal IgA-Producing Cells Regulate Neuroinflammation via IL-10.

B-Cell Deficiency Lowers Blood Pressure in Mice.

NLRC5 deficiency has a moderate impact on immunodominant CD8 T-cell responses during rotavirus infection of adult mice.

c-Myb Exacerbates Atherosclerosis through Regulation of Protective IgM-Producing Antibody-Secreting Cells.

Multiplexed imaging of immune cells in staged multiple sclerosis lesions by mass cytometry.

Aged hind-limb clasping experimental autoimmune encephalomyelitis models aspects of the neurodegenerative process seen in multiple sclerosis.

Activated leukocyte cell adhesion molecule regulates B lymphocyte migration across central nervous system barriers.

Siponimod therapy implicates Th17 cells in a preclinical model of subpial cortical injury.

Early-life programming of mesenteric lymph node stromal cell identity by the lymphotoxin pathway regulates adult mucosal immunity.

Intestinal protection without T cell help.

Dendritic Cell Subsets in Intestinal Immunity and Inflammation.

A simple protein-based surrogate neutralization assay for SARS-CoV-2.

Plasma Cells: From Cytokine Production to Regulation in Experimental Autoimmune Encephalomyelitis.

Persistence of serum and saliva antibody responses to SARS-CoV-2 spike antigens in COVID-19 patients.

Regulation of neuroinflammation by B cells and plasma cells.

The eIF2α kinase HRI triggers the autophagic clearance of cytosolic protein aggregates.

Gut microbiota-specific IgA B cells traffic to the CNS in active multiple sclerosis.

B cell depletion therapies in autoimmune disease: advances and mechanistic insights.

Stromal Cell-Mediated Coordination of Immune Cell Recruitment, Retention, and Function in Brain-Adjacent Regions.

An "Outside-In" and "Inside-Out" Consideration of Complement in the Multiple Sclerosis Brain: Lessons From Development and Neurodegenerative Diseases.

The Ins and Outs of Central Nervous System Inflammation-Lessons Learned from Multiple Sclerosis.

A totally OSM gift to astrocytes relieves inflammation.

The Impact of Migration on the Gut Metagenome of South Asian Canadians.

Fantastic IgA plasma cells and where to find them.

Complement-associated loss of CA2 inhibitory synapses in the demyelinated hippocampus impairs memory.

Queen's Gambit: B Cell to Follicle.

CCR6 Expression on B Cells Is Not Required for Clinical or Pathological Presentation of MOG Protein-Induced Experimental Autoimmune Encephalomyelitis despite an Altered Germinal Center Response.

The Impact of IgA and the Microbiota on CNS Disease.

The microbiome and IgA nephropathy.

Persistence of T Cell and Antibody Responses to SARS-CoV-2 Up to 9 Months after Symptom Onset.

Accumulation of meningeal lymphocytes correlates with white matter lesion activity in progressive multiple sclerosis.

Immunoglobulin A nephropathy is characterized by anticommensal humoral immune responses.

Neonatal LTβR signaling is required for the accumulation of eosinophils in the inflamed adult mesenteric lymph node.

Systemic and mucosal IgA responses are variably induced in response to SARS-CoV-2 mRNA vaccination and are associated with protection against subsequent infection.

Age-dependent gray matter demyelination is associated with leptomeningeal neutrophil accumulation.

Age-related changes in multiple sclerosis and experimental autoimmune encephalomyelitis.

Guardians of the oral and nasopharyngeal galaxy: IgA and protection against SARS-CoV-2 infection.

Under the influence: environmental factors as modulators of neuroinflammation through the IL-10/IL-10R axis.

TIM-4 Identifies Effector B Cells Expressing An IL-23-Driven Proinflammatory Cytokine Module That Promotes Immune Responses.

Comparison of Omicron breakthrough infection versus monovalent SARS-CoV-2 intramuscular booster reveals differences in mucosal and systemic humoral immunity.

Editorial: Environmental factors in autoimmunity.