Simon J. Boulton

A Meiotic Checkpoint Alters Repair Partner Bias to Permit Inter-sister Repair of Persistent DSBs.

IKKα Kinase Regulates the DNA Damage Response and Drives Chemo-resistance in Cancer.

SLX4IP Antagonizes Promiscuous BLM Activity during ALT Maintenance.

CDK phosphorylation of TRF2 controls t-loop dynamics during the cell cycle.

Synthetic Lethality between DNA Polymerase Epsilon and RTEL1 in Metazoan DNA Replication.

Spotlight on the Replisome: Aetiology of DNA Replication-Associated Genetic Diseases.

TRF2-independent chromosome end protection during pluripotency.

Defective ALC1 nucleosome remodeling confers PARPi sensitization and synthetic lethality with HRD.

Mechanistic Insights into Regulation of the ALC1 Remodeler by the Nucleosome Acidic Patch.

RTEL1 Regulates G4/R-Loops to Avert Replication-Transcription Collisions.

Single-molecule analysis reveals cooperative stimulation of Rad51 filament nucleation and growth by mediator proteins.

Oncogenic herpesvirus KSHV triggers hallmarks of alternative lengthening of telomeres.

Mechanism of mitotic recombination: insights from C. elegans.

Tackling PARP inhibitor resistance.

HELQ is a dual-function DSB repair enzyme modulated by RPA and RAD51.

H3K4 methylation by SETD1A/BOD1L facilitates RIF1-dependent NHEJ.

POLQ seals post-replicative ssDNA gaps to maintain genome stability in BRCA-deficient cancer cells.

Visualization of direct and diffusion-assisted RAD51 nucleation by full-length human BRCA2 protein.

Extraordinary collateral mutagenesis induced by CX-5461.

Micronuclei induced by radiation, replication stress, or chromosome segregation errors do not activate cGAS-STING.