Assessment of DNA Double Strand Break Repair Activity Using High-throughput and Quantitative Luminescence-Based Reporter AssaysDiego Grande *1, Eeson Rajendra *1, Bethany Mason 1, Alessandro Galbiati 1, Simon J. Boulton 1,2, Graeme C. M. Smith 1, Helen M. R. Robinson 1
1Artios Pharma Ltd, Cambridge, 2The Francis Crick Institute, London
We present protocols for the assessment of double strand break repair pathway proficiency in cells using a suite of luminescence-based extrachromosomal reporter substrates.
