Intan Safinar Ismail

Rapid Quantification and Validation of Biomarker Scopoletin in by qNMR and UV-Vis for Herbal Preparation.

Bioassay-guided identification of an anti-inflammatory prenylated acylphloroglucinol from Melicope ptelefolia and molecular insights into its interaction with 5-lipoxygenase.

(20S*,24S*)-25-Hy-droxy-20,24-ep-oxy-A-homo-4-oxadammaran-3-one (Chrysura) isolated from the leaves of Walsura chrysogyne.

Steroids from Dysoxylum grande (Meliaceae) leaves.

Dillenia suffruticosa exhibited antioxidant and cytotoxic activity through induction of apoptosis and G2/M cell cycle arrest.

Chrotacumines E and F, two new chromone-alkaloid analogs from Dysoxylum acutangulum (Meliaceae) leaves.

Dillenia Suffruticosa extract inhibits proliferation of human breast cancer cell lines (MCF-7 and MDA-MB-231) via induction of G2/M arrest and apoptosis.

Chrotacumines G-J, chromone alkaloids from Dysoxylum acutangulum with osteoclast differentiation inhibitory activity.

Effect of Defatted Dabai Pulp Extract in Urine Metabolomics of Hypercholesterolemic Rats.

Chemical profile and antiacetylcholinesterase, antityrosinase, antioxidant and α-glucosidase inhibitory activity of Cynometra cauliflora L. leaves.

Synthesis and docking studies of 2,4,6-trihydroxy-3-geranylacetophenone analogs as potential lipoxygenase inhibitor.

Infrared-metabolomics approach in detecting changes in Andrographis paniculata metabolites due to different harvesting ages and times.

Elucidation of in-vitro anti-inflammatory bioactive compounds isolated from Jatropha curcas L. plant root.

Competing role of bioactive constituents in Moringa oleifera extract and conventional nutrition feed on the performance of Cobb 500 broilers.

Induction of cell cycle arrest and apoptosis by betulinic acid-rich fraction from Dillenia suffruticosa root in MCF-7 cells involved p53/p21 and mitochondrial signalling pathway.

Relationship Between Metabolites Composition and Biological Activities of Phyllanthus niruri Extracts Prepared by Different Drying Methods and Solvents Extraction.

Phytochemicals from Mangifera pajang Kosterm and their biological activities.

Induction of Apoptosis in MCF-7 Cells via Oxidative Stress Generation, Mitochondria-Dependent and Caspase-Independent Pathway by Ethyl Acetate Extract of Dillenia suffruticosa and Its Chemical Profile.

Phytochemical Screening and Acute Oral Toxicity Study of Java Tea Leaf Extracts.

Molecular Docking Analysis of Selected Clinacanthus nutans Constituents as Xanthine Oxidase, Nitric Oxide Synthase, Human Neutrophil Elastase, Matrix Metalloproteinase 2, Matrix Metalloproteinase 9 and Squalene Synthase Inhibitors.

Bioactive Constituents of Zanthoxylum rhetsa Bark and Its Cytotoxic Potential against B16-F10 Melanoma Cancer and Normal Human Dermal Fibroblast (HDF) Cell Lines.

Metabolic and biochemical changes in streptozotocin induced obese-diabetic rats treated with Phyllanthus niruri extract.

Anti-Diabetic Activity and Metabolic Changes Induced by Andrographis paniculata Plant Extract in Obese Diabetic Rats.

Discrimination and Nitric Oxide Inhibitory Activity Correlation of Ajwa Dates from Different Grades and Origin.

Urinary metabolic profiling of cisplatin nephrotoxicity and nephroprotective effects of Orthosiphon stamineus leaves elucidated by H NMR spectroscopy.

Identification of the compositional changes in Orthosiphon stamineus leaves triggered by different drying techniques using H NMR metabolomics.

Stability Study of Algerian Seeds Stored under Different Conditions.

A new pyranoxanthone from Garcinia nervosa.

Urinary metabolomics study on the protective role of Orthosiphon stamineus in Streptozotocin induced diabetes mellitus in rats via H NMR spectroscopy.

Structural characterization and evaluation of prebiotic activity of oil palm kernel cake mannanoligosaccharides.

Characterization of Metabolite Profile in Phyllanthus niruri and Correlation with Bioactivity Elucidated by Nuclear Magnetic Resonance Based Metabolomics.

Comparison of partial least squares and random forests for evaluating relationship between phenolics and bioactivities of Neptunia oleracea.

Acetyl- and O-alkyl- derivatives of β-mangostin from Garcinia mangostana and their anti-inflammatory activities.

Discriminative Analysis of Different Grades of Gaharu (Aquilaria malaccensis Lamk.) via ¹H-NMR-Based Metabolomics Using PLS-DA and Random Forests Classification Models.

A new coumarin from stem bark of Calophyllum wallichianum.

Metabolite characterization of different palm date varieties and the correlation with their NO inhibitory activity, texture and sweetness.

Inhibition of UVB-induced pro-inflammatory cytokines and MMP expression by Zanthoxylum rhetsa bark extract and its active constituent hesperidin.

Metabolite Profiling of the Microalgal Diatom and Correlation with Antioxidant and Nitric Oxide Inhibitory Activities via ¹H NMR-Based Metabolomics.

Metabolomic analysis and biochemical changes in the urine and serum of streptozotocin-induced normal- and obese-diabetic rats.

Solvent Extraction and Identification of Active Anticariogenic Metabolites in L. through ¹H-NMR-Based Metabolomics Approach.

Classification of Raw Stingless Bee Honeys by Bee Species Origins Using the NMR- and LC-MS-Based Metabolomics Approach.

Hits-to-Lead Optimization of the Natural Compound 2,4,6-Trihydroxy-3-geranyl-acetophenone (tHGA) as a Potent LOX Inhibitor: Synthesis, Structure-Activity Relationship (SAR) Study, and Computational Assignment.

Antioxidants and α-glucosidase inhibitors from Neptunia oleracea fractions using H NMR-based metabolomics approach and UHPLC-MS/MS analysis.

NMR metabolomics for evaluating passage number and harvesting effects on mammalian cell metabolome.

Effects of leaf extract on lipopolysaccharide -induced neuroinflammation in rats: A behavioral and H NMR-based metabolomics study.

Extraction and Characterization of Organ Components of the Malaysian Sea Cucumber Yielded Bioactives Exhibiting Diverse Properties.

Comparative study of the antidiabetic potential of twig extracts and compounds from two different locations in Malaysia.

Phytochemical and anti-inflammatory properties of Scurrula ferruginea (Jack) Danser parasitising on three different host plants elucidated by NMR-based metabolomics.

Identification of Antidiabetic Metabolites from L. Twigs by Gas Chromatography-Mass Spectrometry-Based Metabolomics and Molecular Docking Study.

Verification and evaluation of monochloropropanediol (MCPD) esters and glycidyl esters in palm oil products of different regions in Malaysia.

Cytotoxic xanthones isolated from Calophyllum depressinervosum and Calophyllum buxifolium with antioxidant and cytotoxic activities.

H-NMR-based metabolomics to investigate the effects of Phoenix dactylifera seed extracts in LPS-IFN-γ-induced RAW 264.7 cells.

Acetylcholinesterase and α-glucosidase inhibitory compounds from .

UHPLC-ESI-Orbitrap-MS Analysis of Biologically Active Extracts from (Lour.) Merr. and L. Leaves.

H NMR-Based Metabolomics Approach in Investigating the Chemical Profile, Antioxidant and Anti-Inflammatory Activities of Gynura procumbens and Cleome gynandra.

Antioxidant, α-Glucosidase, and Nitric Oxide Inhibitory Activities of Six Algerian Traditional Medicinal Plant Extracts and H-NMR-Based Metabolomics Study of the Active Extract.

Potency of Selected Berries, Grapes, and Citrus Fruit as Neuroprotective Agents.

Metabolite Profiles of Red and Yellow Watermelon () Cultivars Using a H-NMR Metabolomics Approach.

Comprehensive GCMS and LC-MS/MS Metabolite Profiling of .

Mass Spectrometry-Based Metabolomics Combined with Quantitative Analysis of the Microalgal Diatom ().

Intermittent Fasting Enhanced the Cognitive Function in Older Adults with Mild Cognitive Impairment by Inducing Biochemical and Metabolic changes: A 3-Year Progressive Study.

The anti-neuroinflammatory effects of Clinacanthus nutans leaf extract on metabolism elucidated through 1H NMR in correlation with cytokines microarray.

Urine Untargeted Metabolomic Profiling Is Associated with the Dietary Pattern of Successful Aging among Malaysian Elderly.

NMR and LCMS analytical platforms exhibited the nephroprotective effect of Clinacanthus nutans in cisplatin-induced nephrotoxicity in the in vitro condition.

Anti-inflammatory evaluation of Scurrula ferruginea (jack) danser parasitizing on Tecoma stans (L.) H.B.K. in LPS/IFN-γ-induced RAW 264.7 macrophages.

Potential of Using Ginger Essential Oils-Based Nanotechnology to Control Tropical Plant Diseases.

Serum Metabolomics Profiling of Commercially Mixed Functional Foods-Effects in Beta-Amyloid Induced Rats Measured Using H NMR Spectroscopy.

Quality of Dabai Pulp Oil Extracted by Supercritical Carbon Dioxide and Supplementation in Hypercholesterolemic Rat-A New Alternative Fat.

Hepatoprotective Effect of Supercritical Carbon Dioxide Extracted Dabai Pulp Oil and Its Defatted Pulp.

Perturbations in Amino Acid Metabolism in Reserpine-Treated Zebrafish Brain Detected by H Nuclear Magnetic Resonance-Based Metabolomics.

H NMR-based metabolomics and UHPLC-ESI-MS/MS for the investigation of bioactive compounds from Lupinus albus fractions.

Evaluation of Indonesian mangrove Xylocarpus granatum leaves ethyl acetate extract as potential anticancer drug.

Complementary Analytical Platforms of NMR Spectroscopy and LCMS Analysis in the Metabolite Profiling of .

Rapid characterisation of xanthine oxidase inhibitors from the flowers of Chrysanthemum morifolium Ramat. Using metabolomics approach.

Multi-Platform Metabolomics Analyses Revealed the Complexity of Serum Metabolites in LPS-Induced Neuroinflammed Rats Treated with Aqueous Extract.

Ginger Essential Oils-Loaded Nanoemulsions: Potential Strategy to Manage Bacterial Leaf Blight Disease and Enhanced Rice Yield.

Clitorienolactones and Isoflavonoids of Roots Alleviate Stress-Like Symptoms in a Reserpine-Induced Zebrafish Model.

Investigation of Andrographolide Effect on Non-Infected Red Blood Cells Using the H-NMR-Based Metabolomics Approach.

An insight on the future therapeutic application potential of Stevia rebaudiana Bertoni for atherosclerosis and cardiovascular diseases.

Preliminary Evaluation of Supercritical Carbon Dioxide Extracted Dabai Pulp Oleoresin as a New Alternative Fat.

Rebaudioside A Enhances LDL Cholesterol Uptake in HepG2 Cells via Suppression of Expression.

Metabolomic Approach for Rapid Identification of Antioxidants in Leaves with Liver Protective Potential.

Synthesis of benzylated amine-substituted xanthone derivatives and their antioxidant and anti-inflammatory activities.

Centella asiatica (L.) Urb. Extract ameliorates branched-chain amino acid (BCAA) metabolism in acute reserpine-induced stress zebrafish model via H Nuclear Magnetic Resonance (NMR)-based metabolomics approach.

Immunomodulatory effects of Isochrysis galbana incorporated diet on Oreochromis sp. (red hybrid tilapia) via Sera-H NMR metabolomics study.

Indonesian Mangrove Leaves Ethanol Extract Is a Potential Super Antioxidant and Anti Methicillin-Resistant Drug.

A Study of the Interaction between Xanthine Oxidase and Its Inhibitors from Using Computational Simulation and Multispectroscopic Methods.

Study on the acute toxicity of sodium taurocholate via zebrafish mortality, behavioral response, and NMR-metabolomics analysis.

Protective effect of Clinacanthus nutans in cisplatin-induced nephrotoxicity on human kidney cell (PCS-400-010) elucidated by an LCMS-based metabolomics approach.

Dietary supplementation of improves the immunity of Asian seabass, (Bloch, 1790) against infection.

Comparative proteome analysis revealed potential biomarkers and the underlying immune mechanisms in Vibrio-resistant hybrid grouper, Epinephelus fuscoguttatus ♀ × Epinephelus lanceolatus ♂.

Impact of diabetes mellitus on osteoarthritis: a scoping review on biomarkers.

H NMR-metabolomics studies on acute toxicity effect of lead in adult zebrafish () model.

Combined knee osteoarthritis and diabetes is associated with reduced muscle strength, physical inactivity, and poorer quality of life.