Matthew H. Wilson
Program in Translational Biology and Molecular Medicine,
Department of Medicine,
Division of Nephrology,
Center for Cell and Gene Therapy,
Department of Medicine, Division of Nephrology
Baylor College of Medicine
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Heterozygous alpha 2A-adrenergic receptor mice unveil unique therapeutic benefits of partial agonists.
Proceedings of the National Academy of Sciences of the United States of America Sep, 2002 | Pubmed ID: 12205290
Functional zinc finger/sleeping beauty transposase chimeras exhibit attenuated overproduction inhibition.
FEBS letters Nov, 2005 | Pubmed ID: 16243318
PiggyBac transposon-mediated gene transfer in human cells.
Molecular therapy : the journal of the American Society of Gene Therapy Jan, 2007 | Pubmed ID: 17164785
Genome-wide mapping of PiggyBac transposon integrations in primary human T cells.
Journal of immunotherapy (Hagerstown, Md. : 1997) Oct, 2009 | Pubmed ID: 19752750
Optimization of the PiggyBac transposon system for the sustained genetic modification of human T lymphocytes.
Journal of immunotherapy (Hagerstown, Md. : 1997) Oct, 2009 | Pubmed ID: 19752751
PiggyBac transposon-based inducible gene expression in vivo after somatic cell gene transfer.
Molecular therapy : the journal of the American Society of Gene Therapy Dec, 2009 | Pubmed ID: 19809403
piggyBac transposon/transposase system to generate CD19-specific T cells for the treatment of B-lineage malignancies.
Human gene therapy Apr, 2010 | Pubmed ID: 19905893
Multiplexed transposon-mediated stable gene transfer in human cells.
Proceedings of the National Academy of Sciences of the United States of America Jan, 2010 | Pubmed ID: 20080581
Designing and testing chimeric zinc finger transposases.
Methods in molecular biology (Clifton, N.J.) , 2010 | Pubmed ID: 20680846
Manipulating piggyBac transposon chromosomal integration site selection in human cells.
Molecular therapy : the journal of the American Society of Gene Therapy Sep, 2011 | Pubmed ID: 21730970
PiggyBac-mediated cancer immunotherapy using EBV-specific cytotoxic T-cells expressing HER2-specific chimeric antigen receptor.
Molecular therapy : the journal of the American Society of Gene Therapy Dec, 2011 | Pubmed ID: 21772253
Combining mTor inhibitors with rapamycin-resistant T cells: a two-pronged approach to tumor elimination.
Molecular therapy : the journal of the American Society of Gene Therapy Dec, 2011 | Pubmed ID: 21878902
Hyperactive piggyBac gene transfer in human cells and in vivo.
Human gene therapy Mar, 2012 | Pubmed ID: 21992617
Loss of glutathione S-transferase A4 accelerates obstruction-induced tubule damage and renal fibrosis.
The Journal of pathology Jun, 2012 | Pubmed ID: 22711583
Evaluating the potential for undesired genomic effects of the piggyBac transposon system in human cells.
Nucleic acids research Feb, 2015 | Pubmed ID: 25605795
piggyBac-ing models and new therapeutic strategies.
Trends in biotechnology Sep, 2015 | Pubmed ID: 26211958
Neurosarcoidosis Presenting as Aseptic Meningitis in an Immunosuppressed Renal Transplant Recipient.
Transplantation Oct, 2016 | Pubmed ID: 26863472
Temporal self-regulation of transposition through host-independent transposase rodlet formation.
Nucleic acids research Jan, 2017 | Pubmed ID: 27899587
piggyBac Transposon System Modification of Primary Human T Cells
Sunandan Saha1,2,
Yozo Nakazawa3,
Leslie E. Huye4,5,
Joseph E. Doherty2,6,
Daniel L. Galvan2,
Cliona M. Rooney4,5,7,
Matthew H. Wilson1,2,4,8
1Program in Translational Biology and Molecular Medicine, Baylor College of Medicine ,
2Department of Medicine, Division of Nephrology, Baylor College of Medicine ,
3Department of Immunology and Pathology, Shinshu University School of Medicine,
4Center for Cell and Gene Therapy, Baylor College of Medicine ,
5Department of Pediatrics, Baylor College of Medicine ,
6Program in Cell and Molecular Biology, Baylor College of Medicine ,
7Department of Molecular Virology and Microbiology, Baylor College of Medicine ,
8, Michael E. DeBakey VA Medical Center
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