Chemical and Biological Engineering Department
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Metabolic engineering of a methylmalonyl-CoA mutase-epimerase pathway for complex polyketide biosynthesis in Escherichia coli.
Biochemistry Apr, 2002 | Pubmed ID: 11955068
A specific role of the Saccharopolyspora erythraea thioesterase II gene in the function of modular polyketide synthases.
Microbiology (Reading, England) Aug, 2003 | Pubmed ID: 12904561
Precursor-Directed polyketide biosynthesis in Escherichia coli.
Bioorganic & medicinal chemistry letters Nov, 2003 | Pubmed ID: 14552761
Biosynthesis of Yersiniabactin, a complex polyketide-nonribosomal peptide, using Escherichia coli as a heterologous host.
Applied and environmental microbiology Nov, 2003 | Pubmed ID: 14602630
Formulation and surface modification of poly(ester-anhydride) micro- and nanospheres.
Biomaterials Jan, 2005 | Pubmed ID: 15207458
Poly(ester-anhydride):poly(beta-amino ester) micro- and nanospheres: DNA encapsulation and cellular transfection.
International journal of pharmaceutics Nov, 2005 | Pubmed ID: 16174553
Improving heterologous polyketide production in Escherichia coli by overexpression of an S-adenosylmethionine synthetase gene.
Applied microbiology and biotechnology Nov, 2007 | Pubmed ID: 17876579
6-deoxyerythronolide B production through chromosomal localization of the deoxyerythronolide B synthase genes in E. coli.
Metabolic engineering Jan, 2008 | Pubmed ID: 17959404
Polyketide analysis using mass spectrometry, evaporative light scattering, and charged aerosol detector systems.
Analytical and bioanalytical chemistry Feb, 2008 | Pubmed ID: 18080862
Bacterial hosts for natural product production.
Molecular pharmaceutics Mar-Apr, 2008 | Pubmed ID: 18232637
A comparison between polymeric microsphere and bacterial vectors for macrophage P388D1 gene delivery.
Pharmaceutical research May, 2008 | Pubmed ID: 18343983
Current status, strategies, and potential for the metabolic engineering of heterologous polyketides in Escherichia coli.
Biotechnology letters Aug, 2008 | Pubmed ID: 18488149
A high-throughput comparison of recombinant gene expression parameters for E. coli-mediated gene transfer to P388D1 macrophage cells.
Journal of biotechnology Oct, 2008 | Pubmed ID: 18694790
Efficient experimental design and micro-scale medium enhancement of 6-deoxyerythronolide B production through Escherichia coli.
Biotechnology progress Sep-Oct, 2009 | Pubmed ID: 19634176
Investigating the role of native propionyl-CoA and methylmalonyl-CoA metabolism on heterologous polyketide production in Escherichia coli.
Biotechnology and bioengineering Feb, 2010 | Pubmed ID: 19806677
Computational analysis of phenotypic space in heterologous polyketide biosynthesis--applications to Escherichia coli, Bacillus subtilis, and Saccharomyces cerevisiae.
Journal of theoretical biology Jan, 2010 | Pubmed ID: 19833139
Metabolic flux analysis and pharmaceutical production.
Metabolic engineering Mar, 2010 | Pubmed ID: 19861167
Utilizing elementary mode analysis, pathway thermodynamics, and a genetic algorithm for metabolic flux determination and optimal metabolic network design.
BMC systems biology , 2010 | Pubmed ID: 20416071
Methods and options for the heterologous production of complex natural products.
Natural product reports Jan, 2011 | Pubmed ID: 21060956
Complete biosynthesis of erythromycin A and designed analogs using E. coli as a heterologous host.
Chemistry & biology Nov, 2010 | Pubmed ID: 21095573
Probing the heterologous metabolism supporting 6-deoxyerythronolide B biosynthesis in Escherichia coli.
Microbial biotechnology May, 2009 | Pubmed ID: 21261933
Multi-factorial engineering of heterologous polyketide production in Escherichia coli reveals complex pathway interactions.
Biotechnology and bioengineering Jun, 2011 | Pubmed ID: 21337322
Simultaneous production and partitioning of heterologous polyketide and isoprenoid natural products in an Escherichia coli two-phase bioprocess.
Journal of industrial microbiology & biotechnology Nov, 2011 | Pubmed ID: 21487833
Analysis of heterologous taxadiene production in K- and B-derived Escherichia coli.
Applied microbiology and biotechnology Feb, 2012 | Pubmed ID: 21850432
Improved E. coli erythromycin A production through the application of metabolic and bioprocess engineering.
Biotechnology progress Jan-Feb, 2012 | Pubmed ID: 21905273
Computational identification of gene over-expression targets for metabolic engineering of taxadiene production.
Applied microbiology and biotechnology Mar, 2012 | Pubmed ID: 22124721
Toward biosynthetic design and implementation of Escherichia coli-derived paclitaxel and other heterologous polyisoprene compounds.
Applied and environmental microbiology Apr, 2012 | Pubmed ID: 22287010
Downstream reactions and engineering in the microbially reconstituted pathway for Taxol.
Applied microbiology and biotechnology May, 2012 | Pubmed ID: 22460591
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