Jordan J. Green

Nanoengineering approaches to the design of artificial antigen-presenting cells.

Biodegradable polymeric vectors for gene delivery to human endothelial cells.

Electrostatic ligand coatings of nanoparticles enable ligand-specific gene delivery to human primary cells.

A Combinatorial Polymer Library Approach Yields Insight into Nonviral Gene Delivery.

Nanoparticles for gene transfer to human embryonic stem cell colonies.

Nanoparticulate delivery of diphtheria toxin DNA effectively kills Mesothelin expressing pancreatic cancer cells.

Poly(beta-amino esters): procedures for synthesis and gene delivery.

Gold, poly(beta-amino ester) nanoparticles for small interfering RNA delivery.

Nanoparticle-delivered suicide gene therapy effectively reduces ovarian tumor burden in mice.

Genetic engineering of human stem cells for enhanced angiogenesis using biodegradable polymeric nanoparticles.

Tissue-specific gene delivery via nanoparticle coating.

Degradable polymers for gene delivery.

Electrostatic surface modifications to improve gene delivery.

The relationship between terminal functionalization and molecular weight of a gene delivery polymer and transfection efficacy in mammary epithelial 2-D cultures and 3-D organotypic cultures.

Drug delivery strategies for therapeutic angiogenesis and antiangiogenesis.

Non-viral gene delivery nanoparticles based on poly(β-amino esters) for treatment of glioblastoma.

Poly(β-amino ester)-DNA complexes: time-resolved fluorescence and cellular transfection studies.

Effects of base polymer hydrophobicity and end-group modification on polymeric gene delivery.

A novel assay for quantifying the number of plasmids encapsulated by polymer nanoparticles.

Synthetic poly(ester amine) and poly(amido amine) nanoparticles for efficient DNA and siRNA delivery to human endothelial cells.

Gene delivery nanoparticles specific for human microvasculature and macrovasculature.

Therapeutic angiogenesis using genetically engineered human endothelial cells.

2011 Rita Schaffer lecture: nanoparticles for intracellular nucleic acid delivery.

Poly(β-amino ester)-nanoparticle mediated transfection of retinal pigment epithelial cells in vitro and in vivo.

Advances in polymeric and inorganic vectors for nonviral nucleic acid delivery.

Cystamine-terminated poly(beta-amino ester)s for siRNA delivery to human mesenchymal stem cells and enhancement of osteogenic differentiation.

Uptake and transfection with polymeric nanoparticles are dependent on polymer end-group structure, but largely independent of nanoparticle physical and chemical properties.

Subtle Changes to Polymer Structure and Degradation Mechanism Enable Highly Effective Nanoparticles for siRNA and DNA Delivery to Human Brain Cancer.

siRNA nanomedicine: the promise of bioreducible materials.

Poly(beta-aminoester) nanoparticle-delivery of p53 has activity against small cell lung cancer in vitro and in vivo.

Student award winner in the Ph.D. category for the 2013 society for biomaterials annual meeting and exposition, april 10-13, 2013, Boston, Massachusetts : biomaterial-mediated cancer-specific DNA delivery to liver cell cultures using synthetic poly(beta-amino ester)s.

The effect and role of carbon atoms in poly(β-amino ester)s for DNA binding and gene delivery.

A bioreducible linear poly(β-amino ester) for siRNA delivery.

(3-aminopropyl)-4-methylpiperazine end-capped poly(1,4-butanediol diacrylate-co-4-amino-1-butanol)-based multilayer films for gene delivery.

Bioengineered nanoparticles for siRNA delivery.

Long-term suppression of ocular neovascularization by intraocular injection of biodegradable polymeric particles containing a serpin-derived peptide.

Independent vs. Cooperative Binding in Polyethylenimine-DNA and Poly(L-lysine)-DNA Polyplexes.

Particle shape dependence of CD8+ T cell activation by artificial antigen presenting cells.

Biomolecule delivery to engineer the cellular microenvironment for regenerative medicine.

Differential polymer structure tunes mechanism of cellular uptake and transfection routes of poly(β-amino ester) polyplexes in human breast cancer cells.

Evaluating the potential of poly(beta-amino ester) nanoparticles for reprogramming human fibroblasts to become induced pluripotent stem cells.

Bioreducible cationic polymer-based nanoparticles for efficient and environmentally triggered cytoplasmic siRNA delivery to primary human brain cancer cells.

Biodegradable polymeric nanoparticles show high efficacy and specificity at DNA delivery to human glioblastoma in vitro and in vivo.

Hypoxia-inducible factors and RAB22A mediate formation of microvesicles that stimulate breast cancer invasion and metastasis.

Highlights from the latest articles in nanomedicine.

Small-Molecule End-Groups of Linear Polymer Determine Cell-type Gene-Delivery Efficacy.

Degradable polymer-coated gold nanoparticles for co-delivery of DNA and siRNA.

An automated multidimensional thin film stretching device for the generation of anisotropic polymeric micro- and nanoparticles.

Polymeric nanoparticles for nonviral gene therapy extend brain tumor survival in vivo.

Shaping the future of nanomedicine: anisotropy in polymeric nanoparticle design.

Platelet-Derived Growth Factor BB Enhances Osteogenesis of Adipose-Derived But Not Bone Marrow-Derived Mesenchymal Stromal/Stem Cells.

Targeted polymeric nanoparticles for cancer gene therapy.

Gene delivery polymer structure-function relationships elucidated via principal component analysis.

Exploring the role of polymer structure on intracellular nucleic acid delivery via polymeric nanoparticles.

Bioreducible Poly(Beta-Amino Ester)s for Intracellular Delivery of SiRNA.

Layer-by-layer inorganic/polymeric nanoparticles for kinetically controlled multigene delivery.

Biodegradable polymer iron oxide nanocomposites: the future of biocompatible magnetism.

Nanoparticle-mediated transcriptional modification enhances neuronal differentiation of human neural stem cells following transplantation in rat brain.

Quantification of cellular and nuclear uptake rates of polymeric gene delivery nanoparticles and DNA plasmids via flow cytometry.

Highlights of Children with Cancer UK's Workshop on Drug Delivery in Paediatric Brain Tumours.

Non-virally engineered human adipose mesenchymal stem cells produce BMP4, target brain tumors, and extend survival.

Non-viral nucleic acid containing nanoparticles as cancer therapeutics.

Synthesis and application of poly(ethylene glycol)-co-poly(β-amino ester) copolymers for small cell lung cancer gene therapy.

Gene delivery nanoparticles to modulate angiogenesis.

Mimicking biological functionality with polymers for biomedical applications.

Noninvasive Targeted Transcranial Neuromodulation via Focused Ultrasound Gated Drug Release from Nanoemulsions.

Tyrosine kinase blocking collagen IV-derived peptide suppresses ocular neovascularization and vascular leakage.

Continuous microfluidic assembly of biodegradable poly(beta-amino ester)/DNA nanoparticles for enhanced gene delivery.

Nanoparticle Tracking Analysis for Determination of Hydrodynamic Diameter, Concentration, and Zeta-Potential of Polyplex Nanoparticles.

Polymeric nanoparticle-based delivery of TRAIL DNA for cancer-specific killing.

Polymeric nanoparticles as cancer-specific DNA delivery vectors to human hepatocellular carcinoma.

A Triple-Fluorophore-Labeled Nucleic Acid pH Nanosensor to Investigate Non-viral Gene Delivery.

Surface engineering for lymphocyte programming.

Biodegradable STING agonist nanoparticles for enhanced cancer immunotherapy.

Therapeutic potential of an anti-angiogenic multimodal biomimetic peptide in hepatocellular carcinoma.

Biomimetic peptide display from a polymeric nanoparticle surface for targeting and antitumor activity to human triple-negative breast cancer cells.

Nanoscale artificial antigen presenting cells for cancer immunotherapy.

Biodegradable Polymeric Nanoparticles for Therapeutic Cancer Treatments.

Anisotropic biodegradable lipid coated particles for spatially dynamic protein presentation.

Injectable drug depot engineered to release multiple ophthalmic therapeutic agents with precise time profiles for postoperative treatment following ocular surgery.

Bacterial tRNase-Based Gene Therapy with Poly(β-Amino Ester) Nanoparticles for Suppressing Melanoma Tumor Growth and Relapse.

Bioreducible Polymeric Nanoparticles Containing Multiplexed Cancer Stem Cell Regulating miRNAs Inhibit Glioblastoma Growth and Prolong Survival.

Non-Viral Delivery To Enable Genome Editing.