Life Science Division
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Chromatin inactivation precedes de novo DNA methylation during the progressive epigenetic silencing of the RASSF1A promoter.
Molecular and cellular biology May, 2005 | Pubmed ID: 15870267
Caspase-independent cytochrome c release is a sensitive measure of low-level apoptosis in cell culture models.
Aging cell Aug, 2005 | Pubmed ID: 16026336
Transcriptional changes associated with breast cancer occur as normal human mammary epithelial cells overcome senescence barriers and become immortalized.
Molecular cancer , 2007 | Pubmed ID: 17233903
Inactivation of p53 function in cultured human mammary epithelial cells turns the telomere-length dependent senescence barrier from agonescence into crisis.
Cell cycle (Georgetown, Tex.) Aug, 2007 | Pubmed ID: 17671422
Stepwise DNA methylation changes are linked to escape from defined proliferation barriers and mammary epithelial cell immortalization.
Cancer research Jun, 2009 | Pubmed ID: 19509227
Molecular distinctions between stasis and telomere attrition senescence barriers shown by long-term culture of normal human mammary epithelial cells.
Cancer research Oct, 2009 | Pubmed ID: 19773443
Role for DNA methylation in the regulation of miR-200c and miR-141 expression in normal and cancer cells.
PloS one , 2010 | Pubmed ID: 20084174
Primary cilium-dependent and -independent Hedgehog signaling inhibits p16(INK4A).
Molecular cell Nov, 2010 | Pubmed ID: 21095584
Self-organization is a dynamic and lineage-intrinsic property of mammary epithelial cells.
Proceedings of the National Academy of Sciences of the United States of America Feb, 2011 | Pubmed ID: 21300877
Epigenetic regulation of normal human mammary cell type-specific miRNAs.
Genome research Dec, 2011 | Pubmed ID: 21873453
Accumulation of multipotent progenitors with a basal differentiation bias during aging of human mammary epithelia.
Cancer research Jul, 2012 | Pubmed ID: 22552289