Aneo Chem-Tech Co., Ltd

1 ARTICLES PUBLISHED IN JoVE

Chemistry

Scaled-Up Preparation of an Intermediate of Upatinib, ACT051-3

Lingling Zhang¹, Weicai Xue¹, Quanwei Li¹, Hui Liu¹, Dexun Xie¹

Here, we present a protocol for the scaled-up synthesis of the intermediate tert-butyl (5-toluenesulfonyl-5h-pyrrole [2,3-b] pyrazine-2-yl) carbamate (ACT051-3) of Upatinib.