Tianjin General Surgery Institute
2 ARTICLES PUBLISHED IN JoVE
Medicine
The Efficacy and Underlying Pathway Mechanisms of ShiDuGao Treatment for Anus Eczema Based on GEO Datasets and Network Pharmacology
Song Wang *1,2,3, Wanyi Xiao *1,2, Anqi He 1,2, Jinyan Jia 1,2, Gang Liu 1,2
1Department of General Surgery, Tianjin Medical University General Hospital, 2Tianjin General Surgery Institute, 3Department of General Surgery, Zibo Municipal Hospital
This investigative effort sought to elucidate the mechanism of topical drug administration using a synergistic integration of network pharmacology and gene expression omnibus (GEO) datasets. This article evaluated the feasibility, target, and mechanism of ShiDuGao (SDG) in treating anus eczema.
Medicine
A Rat Model of Pouchitis Following Proctocolectomy and Ileal Pouch-Anal Anastomosis Using Dextran Sulfate Sodium
Anqi He *1,2, Song Wang *1,2,3, Kaiyu Li 1,2, Baosong Li 1,2,4, Wanyi Xiao 1,2, Gang Liu 1,2
1Department of General Surgery, Tianjin Medical University General Hospital, 2Tianjin General Surgery Institute, 3Department of General Surgery, Zibo Municipal Hospital, 4Department of General Surgery, Binzhou Medical University Hospital
This protocol describes the method for establishing a rat model of pouchitis. The ileal pouch model was created by performing ileal pouch-anal anastomosis (IPAA) surgery using microsurgical techniques. After the surgery, the rat was treated with 4% dextran sulfate sodium (DSS) for 4 days.
