Michigan Medicine, Ann Arbor

1 ARTICLES PUBLISHED IN JoVE

Neuroscience

A Multi-Electrode Array Platform for Modeling Epilepsy Using Human Pluripotent Stem Cell-Derived Brain Assembloids

Tong Pan^1,2, Daniel C. Jaklic^1,2, Shivanshi Vaid^1,2, Grace Lin^1,2, Debora VanHeyningen^1,2, Louis T. Dang^1,2

¹Division of Pediatric Neurology, Department of Pediatrics, Michigan Medicine, Ann Arbor, ²Michigan Neuroscience Institute, University of Michigan, Ann Arbor

This protocol aims to stably plate dorsal-ventral fused assembloids on multi-electrode arrays for modeling epilepsy in vitro.

版权所属 © 2025 MyJoVE 公司版权所有，本公司不涉及任何医疗业务和医疗服务。