登录

Smith and Nephew

1 ARTICLES PUBLISHED IN JoVE

image

Bioengineering

Induction of Adhesion-dependent Signals Using Low-intensity Ultrasound
James Roper 1, Andrew Harrison 2, Mark D. Bass 1
1School of Biochemistry, University of Bristol, 2Smith and Nephew

This protocol describes the stimulation of cultured fibroblasts with low-intensity pulsed ultrasound, which drives focal adhesion formation and Rac1 activation by mimicking engagement of the transmembrane matrix receptor, syndecan-4. This approach allows investigation of a successful clinical technique at the cellular level, thereby providing opportunities for refinement of the therapy.

JoVE Logo

政策

使用条款

隐私

科研

教育

关于 JoVE

版权所属 © 2024 MyJoVE 公司版权所有,本公司不涉及任何医疗业务和医疗服务。