Philips Healthcare

2 ARTICLES PUBLISHED IN JoVE

Medicine

Dual-phase Cone-beam Computed Tomography to See, Reach, and Treat Hepatocellular Carcinoma during Drug-eluting Beads Transarterial Chemo-embolization

Vania Tacher¹, MingDe Lin², Nikhil Bhagat¹, Nadine Abi Jaoudeh³, Alessandro Radaelli⁴, Niels Noordhoek⁴, Bart Carelsen⁴, Bradford J. Wood³, Jean-François Geschwind¹

¹Russell H. Morgan Department of Radiology and Radiological Science, Division of Vascular and Interventional Radiology, The Johns Hopkins Hospital, ²Clinical Informatics, Interventional, and Translational Solutions (CIITS), Philips Research North America, ³Center for Interventional Oncology, Interventional Radiology Section, National Institutes of Health, ⁴Interventional X-ray, Philips Healthcare

Dual-phase cone-beam computed tomography (DP-CBCT) is a useful intraprocedural imaging technique for transarterial chemo-embolization treatment with drug-eluting beads of hepatocellular carcinoma. DP-CBCT has been used to perform three major steps in oncologic interventional radiology: tumor localization (see), navigation and intraprocedural catheter guidance (reach), and intraprocedural evaluation of treatment success (treat).

Medicine

Synthesis and Characterization of Multi-Modal Phase-Change Porphyrin Droplets

Kimoon Yoo^1,2, Alexander Dhaliwal^1,2, Juan Chen¹, Paul S. Sheeran³, Gang Zheng^1,2

¹Princess Margaret Cancer Centre, ²Department of Medical Biophysics, University of Toronto, ³Philips Healthcare

In this protocol, methods for synthesizing and characterizing multi-modal phase-change porphyrin droplets are outlined.