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2 ARTICLES PUBLISHED IN JoVE

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Medicine

Dual-phase Cone-beam Computed Tomography to See, Reach, and Treat Hepatocellular Carcinoma during Drug-eluting Beads Transarterial Chemo-embolization
Vania Tacher 1, MingDe Lin 2, Nikhil Bhagat 1, Nadine Abi Jaoudeh 3, Alessandro Radaelli 4, Niels Noordhoek 4, Bart Carelsen 4, Bradford J. Wood 3, Jean-François Geschwind 1
1Russell H. Morgan Department of Radiology and Radiological Science, Division of Vascular and Interventional Radiology, The Johns Hopkins Hospital, 2Clinical Informatics, Interventional, and Translational Solutions (CIITS), Philips Research North America, 3Center for Interventional Oncology, Interventional Radiology Section, National Institutes of Health, 4Interventional X-ray, Philips Healthcare

Dual-phase cone-beam computed tomography (DP-CBCT) is a useful intraprocedural imaging technique for transarterial chemo-embolization treatment with drug-eluting beads of hepatocellular carcinoma. DP-CBCT has been used to perform three major steps in oncologic interventional radiology: tumor localization (see), navigation and intraprocedural catheter guidance (reach), and intraprocedural evaluation of treatment success (treat).

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Medicine

Synthesis and Characterization of Multi-Modal Phase-Change Porphyrin Droplets
Kimoon Yoo 1,2, Alexander Dhaliwal 1,2, Juan Chen 1, Paul S. Sheeran 3, Gang Zheng 1,2
1Princess Margaret Cancer Centre, 2Department of Medical Biophysics, University of Toronto, 3Philips Healthcare

In this protocol, methods for synthesizing and characterizing multi-modal phase-change porphyrin droplets are outlined.

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