ZF-screens BV

1 ARTICLES PUBLISHED IN JoVE

Immunology and Infection

Establishment and Optimization of a High Throughput Setup to Study Staphylococcus epidermidis and Mycobacterium marinum Infection as a Model for Drug Discovery

Wouter J. Veneman^*1, Rubén Marín-Juez^*2, Jan de Sonneville³, Anita Ordas¹, Susanne Jong-Raadsen², Annemarie H. Meijer¹, Herman P. Spaink¹

¹Institute of Biology, Leiden University, ²ZF-screens BV, ³Life Science Methods BV

This video article describes the high throughput pipeline that has been successfully established to infect and analyze large numbers of zebrafish embryos providing a new powerful tool for compound testing and drug discovery using a whole animal vertebrate organism.