Establishment and Optimization of a High Throughput Setup to Study Staphylococcus epidermidis and Mycobacterium marinum Infection as a Model for Drug DiscoveryWouter J. Veneman *1, Rubén Marín-Juez *2, Jan de Sonneville 3, Anita Ordas 1, Susanne Jong-Raadsen 2, Annemarie H. Meijer 1, Herman P. Spaink 1
1Institute of Biology, Leiden University, 2ZF-screens BV, 3Life Science Methods BV
This video article describes the high throughput pipeline that has been successfully established to infect and analyze large numbers of zebrafish embryos providing a new powerful tool for compound testing and drug discovery using a whole animal vertebrate organism.
