University of Strasbourg

1 ARTICLES PUBLISHED IN JoVE

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Medicine

In vivo Macrophage Imaging Using MR Targeted Contrast Agent for Longitudinal Evaluation of Septic Arthritis
Guillaume Bierry 1,2, Sophie Lefevre 2,3, Jean-Louis Dietemann 1, François Jehl 2,3
1Department of Radiology, University Hospital of Strasbourg, 2EA 3432, University of Strasbourg, 3Department of Bacteriology, University Hospital of Strasbourg

We demonstrate how to perform macrophage MR imaging using ultrasmall superparamagnetic contrast agent (USPIO) in septic arthritis, allowing an initial and longitudinal in vivo non-invasive evaluation of macrophages infiltration and an assessment of therapy efficacy.

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