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Felsenstein Medical Research Center

2 ARTICLES PUBLISHED IN JoVE

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Medicine

Scleral Cross-linking Using Riboflavin and Ultraviolet-A Radiation for Prevention of Axial Myopia in a Rabbit Model
Assaf Dotan 1, Israel Kremer 1,2, Orly Gal-Or 1, Tami Livnat 3, Arie Zigler 4, Dan Bourla 1, Dov Weinberger 1,2,3
1Department of Ophthalmology, Rabin Medical Center, Beilinson Campus, 2Sackler Faculty of Medicine, Tel Aviv University, 3Laboratory of Eye Research, Felsenstein Medical Research Center, 4Racah Institute of Physics, The Hebrew University

We demonstrate the effect of scleral crosslinking with riboflavin and UVA on an axial elongation rabbit eye. Axial elongation was induced in 13 day-old New Zealand rabbits (male and female) by suturing their right eye eyelids (tarsorrhaphy).

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Cancer Research

Establishing 3-Dimensional Spheroids from Patient-Derived Tumor Samples and Evaluating their Sensitivity to Drugs
Neta Moskovits 1,2, Ella Itzhaki 1,2, Nataly Tarasenko 1,2, Eva Chausky 1,2, Avital Bareket-Samish 3, Aleksandr Kaufman 1,2, Raisa Meerson 1,2, Salomon M. Stemmer 1,2,4
1Felsenstein Medical Research Center, 2Davidoff Center, Rabin Medical Center, 3BioInsight Ltd., 4Sackler Faculty of Medicine, Tel Aviv University

The present protocol describes generating 3D tumor culture models from primary cancer cells and evaluating their sensitivity to drugs using cell-viability assays and microscopic examinations.

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