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Felsenstein Medical Research Center

2 ARTICLES PUBLISHED IN JoVE

Medicine

Scleral Cross-linking Using Riboflavin and Ultraviolet-A Radiation for Prevention of Axial Myopia in a Rabbit Model

Assaf Dotan¹, Israel Kremer^1,2, Orly Gal-Or¹, Tami Livnat³, Arie Zigler⁴, Dan Bourla¹, Dov Weinberger^1,2,3

¹Department of Ophthalmology, Rabin Medical Center, Beilinson Campus, ²Sackler Faculty of Medicine, Tel Aviv University, ³Laboratory of Eye Research, Felsenstein Medical Research Center, ⁴Racah Institute of Physics, The Hebrew University

We demonstrate the effect of scleral crosslinking with riboflavin and UVA on an axial elongation rabbit eye. Axial elongation was induced in 13 day-old New Zealand rabbits (male and female) by suturing their right eye eyelids (tarsorrhaphy).

Cancer Research

Establishing 3-Dimensional Spheroids from Patient-Derived Tumor Samples and Evaluating their Sensitivity to Drugs

Neta Moskovits^1,2, Ella Itzhaki^1,2, Nataly Tarasenko^1,2, Eva Chausky^1,2, Avital Bareket-Samish³, Aleksandr Kaufman^1,2, Raisa Meerson^1,2, Salomon M. Stemmer^1,2,4

¹Felsenstein Medical Research Center, ²Davidoff Center, Rabin Medical Center, ³BioInsight Ltd., ⁴Sackler Faculty of Medicine, Tel Aviv University

The present protocol describes generating 3D tumor culture models from primary cancer cells and evaluating their sensitivity to drugs using cell-viability assays and microscopic examinations.