University of Ulsan College of Medicine
2 ARTICLES PUBLISHED IN JoVE
Cancer Research
Functional Assessment of BRCA1 variants using CRISPR-Mediated Base Editors
Ji-Eun See 1,2, Ha Rim Shin 1,2, Gayoung Jang 1,2, Jiyeon Kweon 1,2, Yongsub Kim 1,2
1Department of Biomedical Sciences, Asan Medical Institute of Convergence Science and Technology, Asan Medical Center, University of Ulsan College of Medicine, 2Stem Cell Immunomodulation Research Center, University of Ulsan College of Medicine
People with BRCA1 mutations have a higher risk of developing cancer, which warrants accurate evaluation of the function of BRCA1 variants. Herein, we described a protocol for functional assessment of BRCA1 variants using CRISPR-mediated cytosine base editors that enable targeted C:G to T:A conversion in living cells.
Medicine
Robot-Assisted Kidney Transplantation
Seong Jun Lim 1, Youngmin Ko 1, Dong Hyun Kim 1, Joo Hee Jung 1, Hyunwook Kwon 1, Young Hoon Kim 1, Sung Shin 1
1Division of Kidney and Pancreas Transplantation, Department of Surgery, Asan Medical Center, University of Ulsan College of Medicine
This paper provides technical details for robot-assisted kidney transplantation from a living donor.
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