Nanoscopic Imaging of Human Tissue Sections via Physical and Isotropic ExpansionAleksandra Klimas 1, Octavian Bucur 2, Brigdet Njeri 1, Yongxin Zhao 1
1Department of Biological Sciences, Carnegie Mellon University, 2QPathology
Nanoscale imaging of clinical tissue samples can improve understanding of disease pathogenesis. Expansion pathology (ExPath) is a version of expansion microscopy (ExM), modified for compatibility with standard clinical tissue samples, to explore the nanoscale configuration of biomolecules using conventional diffraction limited microscopes.
