Institute for Basic Science
3 ARTICLES PUBLISHED IN JoVE
Immunology and Infection
Effects of Exposure of Formaldehyde to a Rat Model of Atopic Dermatitis Induced by Neonatal Capsaicin Treatment
Rafael Taeho Han 1, Seung Keun Back 2, JaeHee Lee 1, Hye young Kim 1, Hee Jin Kim 3, Heung Sik Na 1
1Neuroscience Research Institute & Department of Physiology, College of Medicine, Korea University, 2Department of Pharmaceutics and Biotechnology, College of Medical Engineering, Konyang University, 3Division of Biological Science and Technology, Science and Technology College, Yonsei University Wonju Campus
We describe here methods for neonatal capsaicin treatment to induce atopic dermatitis in rats and exposure of vaporized formaldehyde to investigate the effects of formaldehyde inhalation on atopic dermatitis.
Biology
Mucociliary Epithelial Organoids from Xenopus Embryonic Cells: Generation, Culture and High-Resolution Live Imaging
Hae Jin Kang 1, Hye Young Kim 1
1Center for Vascular Research, Institute for Basic Science
We describe a simple protocol to develop mucociliary epithelial organoids from deep ectoderm cells isolated from Xenopus laevis embryos. The multipotent progenitors regenerate epithelial goblet cell precursors and allow live tracking of the initiation and progression of the cell transitions on the surface of organoids.
Neuroscience
µTongue: A Microfluidics-Based Functional Imaging Platform for the Tongue In Vivo
Jisoo Han 1,2, Pyonggang Choi 3, Myunghwan Choi 3
1Department of Biomedical Engineering, Sungkyunkwan University, 2Center for Neuroscience Imaging Research, Institute for Basic Science, 3School of Biological Sciences, Seoul National University
The article introduces the µTongue (microfluidics-on-a-tongue) device for functional taste cell imaging in vivo by integrating microfluidics into an intravital imaging window on the tongue.
