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Institute for Basic Science

3 ARTICLES PUBLISHED IN JoVE

Immunology and Infection

Effects of Exposure of Formaldehyde to a Rat Model of Atopic Dermatitis Induced by Neonatal Capsaicin Treatment

Rafael Taeho Han¹, Seung Keun Back², JaeHee Lee¹, Hye young Kim¹, Hee Jin Kim³, Heung Sik Na¹

¹Neuroscience Research Institute & Department of Physiology, College of Medicine, Korea University, ²Department of Pharmaceutics and Biotechnology, College of Medical Engineering, Konyang University, ³Division of Biological Science and Technology, Science and Technology College, Yonsei University Wonju Campus

We describe here methods for neonatal capsaicin treatment to induce atopic dermatitis in rats and exposure of vaporized formaldehyde to investigate the effects of formaldehyde inhalation on atopic dermatitis.

Biology

Mucociliary Epithelial Organoids from Xenopus Embryonic Cells: Generation, Culture and High-Resolution Live Imaging

Hae Jin Kang¹, Hye Young Kim¹

¹Center for Vascular Research, Institute for Basic Science

We describe a simple protocol to develop mucociliary epithelial organoids from deep ectoderm cells isolated from Xenopus laevis embryos. The multipotent progenitors regenerate epithelial goblet cell precursors and allow live tracking of the initiation and progression of the cell transitions on the surface of organoids.

Neuroscience

µTongue: A Microfluidics-Based Functional Imaging Platform for the Tongue In Vivo

Jisoo Han^1,2, Pyonggang Choi³, Myunghwan Choi³

¹Department of Biomedical Engineering, Sungkyunkwan University, ²Center for Neuroscience Imaging Research, Institute for Basic Science, ³School of Biological Sciences, Seoul National University

The article introduces the µTongue (microfluidics-on-a-tongue) device for functional taste cell imaging in vivo by integrating microfluidics into an intravital imaging window on the tongue.