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Biochemistry

The Automated Crystallography Pipelines at the EMBL HTX Facility in Grenoble
Irina Cornaciu 1,2, Raphael Bourgeas 1, Guillaume Hoffmann 1, Florine Dupeux 1,3, Anne-Sophie Humm 1, Vincent Mariaule 1, Andrea Pica 1,2, Damien Clavel 1,2, Gael Seroul 1,2, Peter Murphy 1, José Antonio Márquez 1,2
1European Molecular Biology Laboratory, 2ALPX S.A.S., 3Institut de Biologie Structurale

Here, we describe how to use the automated macromolecular crystallography pipelines for protein-to-structure, rapid ligand-protein complex analysis and large-scale fragment screening based on the CrystalDirect technology at the HTX Laboratory in EMBL Grenoble.

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