National Chiao Tung University

4 ARTICLES PUBLISHED IN JoVE

JoVE Core

Preparation of Silicon Nanowire Field-effect Transistor for Chemical and Biosensing Applications

Jennifer Yun-Shin Wu¹, Chih-Heng Lin², Mei-Huei Feng¹, Chien-Hung Chen², Ping-Chia Su¹, Po-Wen Yang², Jian-Ming Zheng², Chang-Wei Fu², Yuh-Shyong Yang^1,2

¹Institute of Molecular Medicine and Bioengineering, National Chiao Tung University, ²Department of Biological Science and Technology, National Chiao Tung University

We describe key steps for biosensing by using polysilicon nanowire field-effect transistors, including the preparation of the device and the immobilization and confirmation of a DNA molecular probe on the nanowire surface, as well as conditions for DNA sensing.

Chemistry

Fizzy Extraction of Volatile Organic Compounds Combined with Atmospheric Pressure Chemical Ionization Quadrupole Mass Spectrometry

Hao-Chun Yang¹, Cheng-Hao Chang¹, Pawel L. Urban¹

¹Department of Applied Chemistry, National Chiao Tung University

Fizzy extraction is a new laboratory technique for analysis of volatile and semivolatile compounds. A carrier gas is dissolved in the liquid sample by applying overpressure and stirring the sample. The sample chamber is then decompressed. The analyte species are liberated to the gas phase due to effervescence.

Engineering

A Fabrication and Measurement Method for a Flexible Ferroelectric Element Based on Van Der Waals Heteroepitaxy

Jie Jiang^*1, Yugandhar Bitla^*2, Qiang-xiang Peng¹, Yi-Chun Zhou¹, Ying-Hao Chu³

¹Key Laboratory of Low Dimensional Materials and Application Technology of Ministry of Education, Xiangtan University, ²Department of Physics, Indian Institute of Science, ³Department of Materials Science and Engineering, National Chiao Tung University

In this paper, we present a protocol to directly grow an epitaxial yet flexible lead zirconium titanate memory element on muscovite mica.

Medicine

Synthesis, Characterization, and Application of Superparamagnetic Iron Oxide Nanoprobes for Extrapulmonary Tuberculosis Detection

Chun-Nin Lee¹, Li-Hsuan Chiu^2,5, Chia-Lang Fang³, Shauh-Der Yeh⁴, Chun S. Zuo⁵, Shih-Ching Chen⁶, Li-Kuo Kuo⁷, Yun-Ming Wang⁸, Wen-Fu Thomas Lai^2,5,9

¹Department of Pulmonary and Critical Care Medicine, Taipei Medical University-Shuang Ho Hospital, ²Department of Research and Department of Dentistry, Taipei Medical University / Shuang-Ho Hospital, ³Department of Pathology, Taipei Medical University, ⁴Department of Urology, School of Medicine, College of Medicine, Taipei Medical University, ⁵McLean Imaging Center, McLean Hospital/Harvard Medical School, ⁶Department of Physical Medicine and Rehabilitation, School of Medicine, College of Medicine, Taipei Medical University, ⁷Department of Medicine, Mackay Medical College, ⁸Department of Biological Science and Technology, National Chiao Tung University, ⁹Graduate Institute of Clinical Medicine, Taipei Medical University

To improve serological diagnostic tests for Mycobacterium tuberculosis antigens, we developed superparamagnetic iron oxide nanoprobes to detect extrapulmonary tuberculosis.