INSERM, UMR-S-1172, Centre de Recherche Jean-Pierre Aubert (JPARC)

1 ARTICLES PUBLISHED IN JoVE

Cancer Research

A Detailed Protocol for Characterizing the Murine C1498 Cell Line and its Associated Leukemia Mouse Model

Alexia Mopin¹, Virginie Driss¹, Carine Brinster^1,2

¹Institut pour la Recherche sur le Cancer de Lille (IRCL), INSERM, UMR-S-1172, Centre de Recherche Jean-Pierre Aubert (JPARC), ²Université de Lille

This manuscript provides a technical procedure that can be used to characterize C1498 cell cultures in vitro and the acute leukemia induced in mice after their injection. Phenotypic and functional analyses are performed using flow cytometry, immunofluorescence microscopy, cytochemistry and May-Grünwald Giemsa staining.