A Detailed Protocol for Characterizing the Murine C1498 Cell Line and its Associated Leukemia Mouse ModelAlexia Mopin 1, Virginie Driss 1, Carine Brinster 1,2
1Institut pour la Recherche sur le Cancer de Lille (IRCL), INSERM, UMR-S-1172, Centre de Recherche Jean-Pierre Aubert (JPARC), 2Université de Lille
This manuscript provides a technical procedure that can be used to characterize C1498 cell cultures in vitro and the acute leukemia induced in mice after their injection. Phenotypic and functional analyses are performed using flow cytometry, immunofluorescence microscopy, cytochemistry and May-Grünwald Giemsa staining.