Development of a Hepatitis B Virus Reporter System to Monitor the Early Stages of the Replication CycleHironori Nishitsuji 1, Hiromi Yamamoto 1, Ritsuko Shiina 1, Keisuke Harada 2, Saneyuki Ujino 1, Kunitada Shimotohno 1
1Research Center for Hepatitis and Immunology, National Center for Global Health and Medicine, 2Central Pharmaceutical Research Institute, Japan Tobacco Inc.
Here we describe a newly developed hepatitis B virus (HBV) reporter system to monitor the early stages of the HBV life cycle. This simplified in vitro system will aid in the screening of anti-HBV agents using a high-throughput strategy.
