Clement J. Zablocki Veterans Affairs Medical Center
2 ARTICLES PUBLISHED IN JoVE
Immunology and Infection
Vasodilation of Isolated Vessels and the Isolation of the Extracellular Matrix of Tight-skin Mice
Dorothee Weihrauch 1, John G. Krolikowski 1,2, Deron W. Jones 3, Tahniyath Zaman 3, Omoshalewa Bamkole 1, Janine Struve 4, Paul S. Pagel 5, Nicole L. Lohr 6, Kirkwood A. Pritchard, Jr. 3
1Department of Anesthesiology, Medical College of Wisconsin, 2Clement J. Zablocki Veterans Affairs Medical Center, 3Department of Surgery, Division of Pediatric Surgery, Children's Research Institute, 4Department of Orthopedic Surgery, Medical College of Wisconsin, 5Deptarment of Anesthesiology, Clement J Zblocki Veteran Affairs Medical Center, 6Department of Medicine, Division of Cardiology, Medical College of Wisconsin
We describe the isolation of cardiac extracellular matrix from C57Bl/6J control mice, tight-skin mice, and tight-skin mice treated with the IRF5 inhibitory peptide. We also describe the vasodilation studies on the isolated vessels from C57Bl/6J, tight-skin mice and tight-skin mice treated with the IRF5 inhibitory peptide.
Medicine
Noninvasive Determination of Vortex Formation Time Using Transesophageal Echocardiography During Cardiac Surgery
Paul S. Pagel 1, Lonnie Dye III 2, Graham E.D. Hill 2, Juan L. Vega 2, Justin N. Tawil 2, Derek J. De Vry 2, Kiran Chandrashekarappa 1, Zafar Iqbal 1, Brent T. Boettcher 1, Julie K. Freed 2
1Anesthesia Service, Clement J. Zablocki Veterans Affairs Medical Center, 2Department of Anesthesiology, Medical College of Wisconsin
We describe a protocol to measure vortex formation time, an index of left ventricular filling efficiency, using standard transesophageal echocardiography techniques in patients undergoing cardiac surgery. We apply this technique to analyze vortex formation time in several groups of patients with differing cardiac pathologies.
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