LMU München
2 ARTICLES PUBLISHED IN JoVE
Neuroscience
A Visual Guide to Sorting Electrophysiological Recordings Using 'SpikeSorter'
Nicholas V. Swindale 1, Catalin Mitelut 1, Timothy H. Murphy 2, Martin A. Spacek 1,3
1Ophthalmology and Visual Sciences, University of British Columbia, 2Department of Psychiatry, University of British Columbia, 3Neurobiology, Biology II, LMU München
The article shows how to use the program SpikeSorter to detect and sort spikes in extracellular recordings made with multi-electrode arrays.
Bioengineering
Metabolic Glycoengineering of Sialic Acid Using N-acyl-modified Mannosamines
Paul R. Wratil 1,2, Rüdiger Horstkorte 3
1Max von Pettenkofer-Institut & Genzentrum, Virologie, Nationales Referenzzentrum für Retroviren, Medizinische Fakultät, LMU München, 2Institut für Laboratoriumsmedizin, klinische Chemie und Pathobiochemie, Charité - Universitätsmedizin Berlin, 3Institut für Physiologische Chemie, Martin-Luther-Universität Halle-Wittenberg
Sialic acid is a typical monosaccharide-unit found in glycoconjugates. It is involved in a plethora of molecular and cellular interactions. Here we present a method to modify cell surface sialic acid expression using metabolic glycoengineering with N-acetylmannosamine derivatives.
