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Fondazione IRCCS Ca' Granda - Ospedale Maggiore Policlinico
2 ARTICLES PUBLISHED IN JoVE
Immunology and Infection
Building Up a High-throughput Screening Platform to Assess the Heterogeneity of HER2 Gene Amplification in Breast Cancers
Giulia Ercoli 1, Gianluca Lopez 1,2, Camilla Ciapponi 1,3, Chiara Corti 1,2, Luca Despini 4, Donatella Gambini 5, Letterio Runza 1, Concetta Blundo 4, Amedeo Sciarra 1, Nicola Fusco 1,6
1Division of Pathology, Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico, 2School of Medicine, University of Milan, 3School of Biology, University of Pavia, 4Division of Breast Surgery, Fondazione IRCCS Ca' Granda - Ospedale Maggiore Policlinico, 5Division of Medical Oncology, Fondazione IRCCS Ca' Granda - Ospedale Maggiore Policlinico, 6Department of Biomedical, Surgical, and Dental Sciences, University of Milan
Heterogeneous distribution of HER2-positive cells can be observed in a subset of breast cancers and generates clinical dilemmas. Here, we introduce a reliable and cost-effective protocol to define, quantify, and compare HER2 intra-tumor genetic heterogeneity in a large series of heterogeneously processed breast cancers.
Medicine
Integrating Augmented Reality Tools in Breast Cancer Related Lymphedema Prognostication and Diagnosis
Marco Invernizzi 1, Letterio Runza 2, Alessandro De Sire 1, Lorenzo Lippi 1, Concetta Blundo 3, Donatella Gambini 4, Renzo Boldorini 5,6, Stefano Ferrero 2,7, Nicola Fusco 2,7
1Physical and Rehabilitative Medicine, Department of Health Sciences, University of Eastern Piedmont "A. Avogadro", 2Division of Pathology, Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico, 3Division of Breast Surgery, Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico, 4Division of Medical Oncology, Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico, 5Division of Pathology, Maggiore della Carità Hospital, 6Department of Health Sciences, University of Eastern Piedmont "A. Avogadro", 7Department of Biomedical, Surgical, and Dental Sciences, University of Milan
Breast cancer related lymphedema is frequent in breast cancer survivors, but there are not widely employed guidelines for its diagnosis and quantification. Here, we introduce a reliable and cost-effective protocol to define, quantify, and compare upper limb volume in breast cancer patients.
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